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[[Farre Lab:Research |<h3><font style="color:#228B22;">Research</font></h3>]]
[[Farre Lab:Research |<h3><font style="color:#228B22;">Research</font></h3>]]


Our goal is to understand how circadian clocks work and why they play such a key role in growth and development.  
Our goal is to understand how circadian clocks work and why they play such an important role in growth and stress responses. We study the regulation and role of circadian rhythms in plants and algae. Circadian rhythms are necessary for optimal growth and survival in several photosynthetic species, including ''Chlamydomonas rheinhardtii'', ''Synechocystes'' sp. and ''Arabidopsis thaliana''. Although circadian clocks share a basic architecture, they differ in their molecular components and appear not to be conserved between different taxa.  


We study the regulation and role of circadian rhythms in plants, which as sessile and autotrophic organisms rely heavily on daily and seasonal changes for their development and growth. Recent findings show that the appropriate resonance of internal rhythms with daily environmental rhythms optimizes plant growth and survival. During the last few years, a large number of clock components have been identified in plants. However, knowledge of the molecular mechanisms involved in plant circadian clocks lags behind studies in other organisms such as Drosophila and Cyanobacteria. Although circadian clocks share a basic architecture among different taxa, they differ in their molecular components. Thus the study of circadian rhythms in plants will help define not only their role on plant specific processes but also the design principles of circadian oscillators.  
We work on the model plant ''Arabidopsis thaliana'' and have recently started analyzing rhythms in the heterokont alga ''Nannochloropsis oceanica''.  


[[Farre_Lab:Research | read more...]]
[[Farre_Lab:Research | read more...]]
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*[[Farre_Lab:Eva_Farre|Eva Farre]]
*[[Farre_Lab:Eva_Farre|Eva Farre]]
*[[Farre_Lab:Tomomi Takeuchi|Tomomi Takeuchi]]
*[[Farre_Lab:Laura Schroeder|Laura Schroeder]]
*[[Farre_Lab:Linsey Newton|Linsey Newton]]
*[[Farre_Lab:Linsey Newton|Linsey Newton]]
*[[Farre_Lab:Jenny Carlsson|Jenny Carlsson]]
*[[USer:Eric R Poliner|Eric Poliner]]
*[[Farre_Lab:Tiffany Liu|Tiffany Liu]]
*[[Farre_Lab: Cameron Cummings|Cameron Cummings]]
*[[Farre_Lab:Jonathan Diehl|Jonathan Diehl]]
*[[Farre_Lab: Lauren Bedro|Lauren Bedro]]
*[[Farre_Lab:Open_positions|Open Positions:
*[[Farre_Lab: Traverse Cottrell|Traverse Cottrell]]
GRADUATE STUDENT]]
*[[Farre_Lab:Open_positions|Open Positions: graduate student]]
 
 


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[[Farre_Lab:Publications |<h3><font style="color:#F8B603;">Publications</font></h3>]]
[[Farre_Lab:Publications |<h3><font style="color:#F8B603;">Publications</font></h3>]]
 
*Poliner E, Zienkiewicz K, Pullman J, Newton L, Benning C, Farré EM. A toolkit for Nannochloropsis oceanica CCMP1779 enables gene stacking and genetic engineering of the eicosapentaenoic acid pathway for enhanced fatty acid production. Plant Biotechnology Journal (in press) [https://www.ncbi.nlm.nih.gov/pubmed/28605577 Pubmed]
*Farre EM and Kay SA (2007) PRR7 Protein levels are regulated by light and the circadian clock in Arabidopsis. Plant J 52 (3):548–560.
*Zienkiewicz K, Zienkiewicz A, Poliner E, Du ZY, Vollheyde K, Herrfurth C, Marmon S, Farré EM, Feussner I, Benning C (2017). Nannochloropsis, a rich source of diacylglycerol acyltransferases for engineering of triacylglycerol content in different hosts. Biotechnology for Biofuels 10:8 [https://www.ncbi.nlm.nih.gov/pubmed/28070221 Pubmed]
 
*Liu T, Newton L, Liu MJ, Shiu SH, Farre EM. A G-box-like motif is necessary for transcriptional regulation by circadian pseudo-response regulators in Arabidopsis(2016) Plant Physiology 170(1):528-39 [http://www.ncbi.nlm.nih.gov/pubmed/26586835  PubMed].  
*Para A, Farre EM, Imaizumi T, Pruneda-Paz J, Harmon FG, Kay SA (2007). PRR3 is a vascular regulator of TOC1 stability in the Arabidopsis circadian clock. Plant Cell 19:3462-3473.
'''NOTE:''' An updated corrected version of the manuscript has been published online (Jan. 20, 2016)
 
*Poliner E, Panchy N, Newton L, Wu G, Lapinsky A, Bullard B, Zienkiewicz A, Benning C, Shiu S-H, Farré EM (2015) Transcriptional coordination of physiological responses in ''Nannochloropsis oceanica'' CCMP1779 under light/dark cycles. Plant J. 83(6):1097-113 [http://www.ncbi.nlm.nih.gov/pubmed/26216534 Pubmed]
*Zeilinger MN, Farre EM, Taylor SR, Kay SA and Doyle FJ III (2006) A novel computational model of the circadian clock in Arabidopsis that incorporates PRR7 and PRR9. Mol Syst Biol 2: 58.
*Horak E, Farré EM (2015)The regulation of UV-B responses by the circadian clock. Plant Signaling and Behavior 10(5):e1000164.
 
*Takeuchi T, Newton L, Burkhardt A, Mason S, Farre EM (2014) Light and the circadian clock mediate time specific changes in sensitivity to UV-B stress under light/dark cycles. Journal of Experimental Botany 65(20):6003-12 [http://www.ncbi.nlm.nih.gov/pubmed/25147271 PubMed]
*Farre EM, Harmer SL, Harmon FG, Yanovsky MJ, Kay SA.  (2005) Overlapping and distinct roles of PRR7 and PRR9 in the Arabidopsis circadian clock. Curr Biol 15(1):47-54.  
*Braun R, Farré EM, Schurr U, Matsubara S (2014) Effects of light and circadian clock on growth and chlorophyll accumulation of Nannochloropsis gaditana. Journal of Phycology 50(1):515–525 [http://onlinelibrary.wiley.com/doi/10.1111/jpy.12177/abstract]
 
*Liu T, Carlsson J, Takeuchi T, Newton L (2013) Direct regulation of abiotic responses by the Arabidopsis circadian clock component PRR7. Plant J 76(1):101-14[http://www.ncbi.nlm.nih.gov/pubmed/23808423 PubMed]
*Farré EM, Liu T (2013) The PRR family of transcriptional regulators reflects the complexity and evolution of plant circadian clocks. Curr Opin Plant Biol 16(5):621-9[http://www.ncbi.nlm.nih.gov/pubmed/23856081 PubMed]




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[[Farre_Lab:Research |<h3><font style="color:#F8B603;">Announcements</font></h3>]]
[[Farre_Lab:Research |<h3><font style="color:#F8B603;">Announcements</font></h3>]]
*'''Congratulations Cameron for his Poster Award at the Spring University Undergraduate Research and Arts Forum '''!
* We are looking for rotation students interested in working on rhythms.
*[[Farre_Lab:Announcements | Group meeting, journal clubs, and seminars]]<br>
*[[Farre_Lab:Announcements | Group meeting, journal clubs, and seminars]]<br>


*CONGRATULATIONS TOMOMI: Tomomi Takeuchi has been awarded the "2010 Richard L. Anderson Endowed Undergraduate Prize" and has received a Summer 2010 CNS Undergraduate Research Support Scholarship.
 
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[[Farre_Lab:Links |<h3><font style="color:red">Links</font></h3>]]
[[Farre_Lab:Links |<h3><font style="color:red">Links</font></h3>]]
*[https://sites.google.com/a/msu.edu/research-teaching-msu/ Farre Lab NSF funded Teaching & Research program for pre-service teachers]
*[[Farre_Lab:Links|MSU Links]]
*[[Farre_Lab:Links|MSU Links]]
*[[Farre_Lab:Links|For Graduate students]]
*[[Farre_Lab:Links|Other Circadian Labs]]
*[[Farre_Lab:Links|Other Circadian Labs]]
*[http://plantgenomics.msu.edu Plant Genomics Undergraduate Program at MSU]
*[[Farre_Lab:Links|Tools]]
*[[Farre_Lab:Links|Tools]]
*[[Farre_Lab:Links|Other Interesting Links]]
*[[Farre_Lab:Links|Other Interesting Links]]
*[[Farre_Lab:Links|Rhythm Movies]]
*[[Farre_Lab:Links|Rhythm Movies]]
*[http://www.hulu.com/watch/16417/saturday-night-live-googly-eyes-gardener| Gardening Tips]
*[http://www.hulu.com/watch/16417/saturday-night-live-googly-eyes-gardener| Plant humor: Gardening Tips]
*http://www.openwetware.org http://openwetware.org/images/0/01/80x15_openwetware.png
*http://www.openwetware.org http://openwetware.org/images/0/01/80x15_openwetware.png
 
<h3><font style="color:red">Funding</font></h3>
*NSF
*MSU
__NOTOC__
__NOTOC__

Revision as of 06:31, 19 June 2017


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Research

Our goal is to understand how circadian clocks work and why they play such an important role in growth and stress responses. We study the regulation and role of circadian rhythms in plants and algae. Circadian rhythms are necessary for optimal growth and survival in several photosynthetic species, including Chlamydomonas rheinhardtii, Synechocystes sp. and Arabidopsis thaliana. Although circadian clocks share a basic architecture, they differ in their molecular components and appear not to be conserved between different taxa.

We work on the model plant Arabidopsis thaliana and have recently started analyzing rhythms in the heterokont alga Nannochloropsis oceanica.

read more...

Lab Members

Publications

  • Poliner E, Zienkiewicz K, Pullman J, Newton L, Benning C, Farré EM. A toolkit for Nannochloropsis oceanica CCMP1779 enables gene stacking and genetic engineering of the eicosapentaenoic acid pathway for enhanced fatty acid production. Plant Biotechnology Journal (in press) Pubmed
  • Zienkiewicz K, Zienkiewicz A, Poliner E, Du ZY, Vollheyde K, Herrfurth C, Marmon S, Farré EM, Feussner I, Benning C (2017). Nannochloropsis, a rich source of diacylglycerol acyltransferases for engineering of triacylglycerol content in different hosts. Biotechnology for Biofuels 10:8 Pubmed
  • Liu T, Newton L, Liu MJ, Shiu SH, Farre EM. A G-box-like motif is necessary for transcriptional regulation by circadian pseudo-response regulators in Arabidopsis(2016) Plant Physiology 170(1):528-39 PubMed.

NOTE: An updated corrected version of the manuscript has been published online (Jan. 20, 2016)

  • Poliner E, Panchy N, Newton L, Wu G, Lapinsky A, Bullard B, Zienkiewicz A, Benning C, Shiu S-H, Farré EM (2015) Transcriptional coordination of physiological responses in Nannochloropsis oceanica CCMP1779 under light/dark cycles. Plant J. 83(6):1097-113 Pubmed
  • Horak E, Farré EM (2015)The regulation of UV-B responses by the circadian clock. Plant Signaling and Behavior 10(5):e1000164.
  • Takeuchi T, Newton L, Burkhardt A, Mason S, Farre EM (2014) Light and the circadian clock mediate time specific changes in sensitivity to UV-B stress under light/dark cycles. Journal of Experimental Botany 65(20):6003-12 PubMed
  • Braun R, Farré EM, Schurr U, Matsubara S (2014) Effects of light and circadian clock on growth and chlorophyll accumulation of Nannochloropsis gaditana. Journal of Phycology 50(1):515–525 [1]
  • Liu T, Carlsson J, Takeuchi T, Newton L (2013) Direct regulation of abiotic responses by the Arabidopsis circadian clock component PRR7. Plant J 76(1):101-14PubMed
  • Farré EM, Liu T (2013) The PRR family of transcriptional regulators reflects the complexity and evolution of plant circadian clocks. Curr Opin Plant Biol 16(5):621-9PubMed


see complete list...

Announcements

  • Congratulations Cameron for his Poster Award at the Spring University Undergraduate Research and Arts Forum !
  • We are looking for rotation students interested in working on rhythms.
  • Group meeting, journal clubs, and seminars


Links

Funding

  • NSF
  • MSU