Farre Lab

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Research

Our goal is to understand how circadian clocks work and why they play such a key role in growth and development.

We study the regulation and role of circadian rhythms in plants, which as sessile and autotrophic organisms rely heavily on daily and seasonal changes for their development and growth. Recent findings show that the appropriate resonance of internal rhythms with daily environmental rhythms optimizes plant growth and survival. During the last few years, a large number of clock components have been identified in plants. However, knowledge of the molecular mechanisms involved in plant circadian clocks lags behind studies in other organisms such as Drosophila and Cyanobacteria. Although circadian clocks share a basic architecture among different taxa, they differ in their molecular components. Thus the study of circadian rhythms in plants will help define not only their role on plant specific processes but also the design principles of circadian oscillators.

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  • Lab Members


Publications

  • Filiault DL, Wessinger CA, Dinneny JR, Lutes J, Borevitz JO, Weigel D, Chory J and Maloof JN. (2008) Amino acid polymorphisms in Arabidopsis phytochrome B cause differential responses to light. PNAS 105, 3157-3162.
  • Nozue K, Covington MF, Duek PD, Lorrain S, Fankhauser C, Harmer SL, Maloof JN. (2007) Rhythmic growth explained by coincidence between internal and external cues. Nature 448, 358-361.
  • Balasubramanian, S., Sureshkumar, S., Agrawal, M., Michael, T.P., Wessinger, C., Maloof, J.N., Clark, R., Warthmann, N., Chory, J., Weigel, D. (2006) The PHYTOCHROME C photoreceptor gene mediates natural variation in flowering and growth responses of Arabidopsis thaliana. Nat Genet 38, 711-5.

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