Frankel

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Welcome to the Frankel Group

Biological interfaces possess intriguing properties related to their function, an understanding of which can lead to treatments of disease, development of sophisticated medical implants and construction of bio/machine devices. Our particular expertise is in both investigating the fundamental science of these interfaces as well as trying to exploit them to build devices.

Specifically we are looking at the following systems:

Cyberplasm - A part biological / part machine swimming robot

▪. The Cell Membrane - how do signals, biochemical and physical in origin, transmit through the cell membrane in order to control the cells machinery. Our ultimate goal in this area is to develop a new model of cell membrane structure and function.

▪. The Cell/Machine Interface- In this collaborative international project we are building a swimming biohybrid robot and in the process developing methods for encouraging cells to talk to electronics

▪. Interfaces Involved in Disease - Cancer cell adhesion to the tumour surface results in tumour growth. We would like to be able to understand and manipulate such surfaces to prevent tumor growth and treat the disease.

▪. Self Assembly of Small Biomolecules - Here we are trying to exploit self assembly in order to create nanoscale structures with potential technological applications

▪. Surfaces and Their Role in the Origin of Life on Earth

We work at the interface between chemistry, biology and physics and employ both experimental and theoretical approaches. If you are interested in studying challenging systems involving complexity and are not afraid of inter-disciplinary work please don’t hesitate to contact me. Dr. Daniel Frankel : d.j.frankel@newcastle.ac.uk

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LATEST NEWS !!

Welcome to the lab to 3 new undergrad research students Cherie Pham, Daniel Crane and Hani Salam

Cyberplasm receives media attention, here is the original press release living microrobot

Congratulations to Orr Yarkoni for passing his PhD viva for a thesis entitled "Engineering an inducible NO pathway to facilitate cell-electronics communication"

Congratulations to Darman Nordin for passing his PhD viva for a thesis entitled "Interaction of the extracellular matrix protein fibronectin with model cell membranes"