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== '''Welcome to the Frankel Group''' == | == '''Welcome to the Frankel Group''' == | ||
We are interested in the | We are interested in the reductionist approach to biology which considers complex biological systems as machines allowing us to apply the laws of physics and rules of engineering to understand such systems. In particular we are working on building bio/machine hybrids bringing biological sensitivity and control to robotic devices. We are also interested in constructing artificial viruses for drug delivery (without the nasty infectious bits!!) and understanding/exploiting the ultimate bio/machine interface, the cell membrane. <br> | ||
▪. '''Unfolding Disease One Molecule at a Time''' - '' Proteins involved in disease such as HIV, cancer and arthritis are potential therapeutic targets. Their unfolding and self assembly behaviour is examined at the single molecule level revealing insight into their function.'' <br> | ▪. '''Unfolding Disease One Molecule at a Time''' - '' Proteins involved in disease such as HIV, cancer and arthritis are potential therapeutic targets. Their unfolding and self assembly behaviour is examined at the single molecule level revealing insight into their function.'' <br> |
Revision as of 07:56, 23 June 2013
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Home=Frankel
Members=#,Principal Investigator=Frankel:Lab_Members, PhD students=Frankel:Lab_Members, Alumni=Frankel:Lab_Members
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Publications=Frankel:Publications
Lab=Frankel:Research
Research=#,Force Spectroscopy=Frankel:Force Spectroscopy,HIV/Virus=Frankel:HIV/Virus,ECM Proteins=Frankel:ECM Proteins,Cyberplasm=Frankel:Cyberplasm,Cancer=Frankel:Cancer
Welcome to the Frankel GroupWe are interested in the reductionist approach to biology which considers complex biological systems as machines allowing us to apply the laws of physics and rules of engineering to understand such systems. In particular we are working on building bio/machine hybrids bringing biological sensitivity and control to robotic devices. We are also interested in constructing artificial viruses for drug delivery (without the nasty infectious bits!!) and understanding/exploiting the ultimate bio/machine interface, the cell membrane. ▪. Unfolding Disease One Molecule at a Time - Proteins involved in disease such as HIV, cancer and arthritis are potential therapeutic targets. Their unfolding and self assembly behaviour is examined at the single molecule level revealing insight into their function. We work at the interface between chemistry, biology and physics and employ both experimental and theoretical approaches. If you are interested in studying challenging systems involving complexity and are not afraid of inter-disciplinary work please don’t hesitate to contact me. Dr. Daniel Frankel : d.j.frankel@newcastle.ac.uk |
LATEST NEWS !!HIV paper makes front cover of Soft Matter: Biorobot paper accepted!! 4 new papers in print related to protein unfolding Welcome to the Lab to new PhD student Ana from Ecuador. Cyberplasm receives media attention, here is the original press release living microrobot Congratulations to Orr Yarkoni for passing his PhD viva for a thesis entitled "Engineering an inducible NO pathway to facilitate cell-electronics communication" Congratulations to Darman Nordin for passing his PhD viva for a thesis entitled "Interaction of the extracellular matrix protein fibronectin with model cell membranes" |