Frankel:Cyberplasm

From OpenWetWare

(Difference between revisions)
Jump to: navigation, search
Current revision (12:16, 2 March 2013) (view source)
 
(10 intermediate revisions not shown.)
Line 3: Line 3:
<br>
<br>
-
''<font align="center" font color=#ffffff font size=8>_________ </font>'''''<font color=#000000 font size=8> Cyberplasm - a biohybrid swimming robot</font>'''
+
''<font align="center" font color=#ffffff font size=8>_________ </font>'''''<font color=#000000 font size=6>Biohybrid Machines </font>'''
<br>
<br>
{| cellspacing="3px"
{| cellspacing="3px"
<div>
<div>
-
|  align="justify" width=21px style="border: 2px solid #000033; background-color:#BDBDBD; padding:1em;" class="plainlinks" valign="top"|
+
|  align="justify" width=400px style="border: 2px solid #000033; background-color:#ffffff; padding:1em;" class="plainlinks" valign="top"|
 +
''<font align="center" font color=#ffffff font size=8>_______ </font>'''''<font color=#000000 font size=3>Cyberplasm</font>'''
-
[[Image:HIV1.png|500px]]
+
<br>
 +
[[Image:Cyberplasm.png|500px]]
</div>
</div>
| align="center" rowspan="2" width=30px style="border: 2px solid #000033; background-color:#ffffff; padding:1em;" valign="top"|
| align="center" rowspan="2" width=30px style="border: 2px solid #000033; background-color:#ffffff; padding:1em;" valign="top"|
 +
<br>
 +
<br>
 +
[[Image:FNselec.png|235px]]
 +
<br>
 +
<br>
-
[[Image:GP160_on_mica.png|235px]]
+
[[Image:FNseleczoom.png|235px]]
-
[[Image:GP160_on_DOPC.png|235px]]
+
<br>
-
[[Image:Pore50nm.png|235px]]
+
<br>
-
[[Image:Pore100nm.png|235px]]
+
-
[[Image:GP160.png|235px]]
+
 +
[[Image:FN_complexes.jpg|235px]]
 +
<br>
 +
<br>
 +
[[Image:FN_adsorbed.jpg|235px]]
{|width="*"
{|width="*"
|
|
Line 38: Line 47:
|}
|}
|-
|-
-
| align="justify" width=21px style="border: 2px dashed #045FB4; background-color:#FFFFFF; padding:1em;" valign="top"|
+
| align="justify" width=21px style="border: 2px solid #000000; background-color:#FFFFFF; padding:1em;" valign="top"|
-
'''<font color=#000000 font size=3>HIV covers its protein capsid with a viral envelop where GP160 is located. This glycoprotein facilitates fusion between the viral membrane and the host -cell membrane allowing liberation of the viral contents into the host cell. GP160 forms a trimer, where each monomer consists in two non-covalently associated subunits: a surface subunit GP120 that recognize and bind to specific receptor on the host cell and a transmembrane subunit GP41 that promotes membrane fusion.</font>'''
+
[[Image:FNint.png|500px]]
-
 
+
-
[[Image:GIF-VIRUS-INFECTION1.gif|500px]]
+
   
   
----
----
-
   
+
'''<font color=#000000 font size=3> One of the major components of the extracellular matrix (ECM) is fibronectin, this dimeric glycoprotein is involved in numerous cell processes and has important functions in vertebrate development.  
-
'''<font color=#000000 font size=3>The images to the right show the self assembly of the HIV gp160 protein reconstituted into DOPC bilayer and adsorbed onto mica. Each pore is made up of 6 features with dimensions consistent with single molecules</font>'''
+
Fibronectin in the extracellular matrix interacts with the transmembrane integrins in a highly specific manner. The ECM ligand protein contains a tripeptide recognition site, Arg-Gly-Asp (RGD), responsible for the affinity of the cell surface receptors with its ligand.
 +
Atomic force microscopy images can be appreciated, these illustrations depict how fibronectin molecules are almost exclusively absorbed on the DPPC domains.

Current revision

Danbanner-bio-machines.jpg



_________ Biohybrid Machines















One of the major components of the extracellular matrix (ECM) is fibronectin, this dimeric glycoprotein is involved in numerous cell processes and has important functions in vertebrate development.

Fibronectin in the extracellular matrix interacts with the transmembrane integrins in a highly specific manner. The ECM ligand protein contains a tripeptide recognition site, Arg-Gly-Asp (RGD), responsible for the affinity of the cell surface receptors with its ligand. Atomic force microscopy images can be appreciated, these illustrations depict how fibronectin molecules are almost exclusively absorbed on the DPPC domains.

Personal tools