Frankel:Force Spectroscopy: Difference between revisions
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'''<font align="center" font color=#ffffff font size=8>______ </font>''''''<font align="center" font color=#000000 font size=8>Force Spectroscopy</font>''' | |||
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'''<font color=#000000 font size=3>Picking up and unfolding a single protein</font>''' | |||
[[Image:Spectroscopy_complete.jpg|350px]] | |||
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'''<font color=#FFFFFF font size=3>Assembly</font>''' | |||
'''<font color=#000000 font size=3>Nano-mechanics of HIV GP160</font>''' | |||
[[Image:GP160mica.png|300px]] | |||
[[Image:GP_160.png|300px]] | |||
'''<font color=#FFFFFF font size=6>GP160mica</font>''' | |||
[[Image:Stlow.png|330px]] | |||
[[Image:Hislow.png|330px]] | |||
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'''<font color=#000000 font size=3 font align="justify"> | |||
Typical sawtooth unfolding pattern of a single molecule of the HIV virion protein GP160. Unfolding forces can be extracted from the sawtooth pattern by applying the worm like chain model.</font>''' | |||
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'''<font color=#000000 font size=3> Unfolding the ECM protein fibronectin </font>''' | |||
[[Image:FNsawt.png|300px]] | |||
[[Image:HisFN.png|300px]] | |||
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Sawtooth pattern on the retraction force curve indicating the unfolding of fibronectin. The average rupture force distribution of the protein on mica surface was 85.1 ± 2.7 pN. | |||
Latest revision as of 18:22, 9 January 2013
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Home=Frankel
Members=#,Principal Investigator=Frankel:Lab_Members, PhD students=Frankel:Lab_Members, Alumni=Frankel:Lab_Members
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Research=#,Force Spectroscopy=Frankel:Force Spectroscopy,HIV/Virus=Frankel:HIV/Virus,ECM Proteins=Frankel:ECM Proteins,Cyberplasm=Frankel:Cyberplasm,Cancer=Frankel:Cancer
'______ 'Force Spectroscopy
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Picking up and unfolding a single protein
|
Assembly Nano-mechanics of HIV GP160
GP160mica
Typical sawtooth unfolding pattern of a single molecule of the HIV virion protein GP160. Unfolding forces can be extracted from the sawtooth pattern by applying the worm like chain model.
| |
|
Unfolding the ECM protein fibronectin
Sawtooth pattern on the retraction force curve indicating the unfolding of fibronectin. The average rupture force distribution of the protein on mica surface was 85.1 ± 2.7 pN. |
