Frankel:HIV/Virus
From OpenWetWare
(Difference between revisions)
Current revision (20:35, 9 January 2013) (view source) |
|||
| (8 intermediate revisions not shown.) | |||
| Line 3: | Line 3: | ||
<br> | <br> | ||
| - | + | ''<font align="center" font color=#ffffff font size=8>_________ </font>'''''<font color=#000000 font size=8>HIV gp160</font>''' | |
| - | + | <br> | |
{| cellspacing="3px" | {| cellspacing="3px" | ||
<div> | <div> | ||
| Line 21: | Line 21: | ||
[[Image:Pore50nm.png|235px]] | [[Image:Pore50nm.png|235px]] | ||
[[Image:Pore100nm.png|235px]] | [[Image:Pore100nm.png|235px]] | ||
| + | [[Image:GP160.png|235px]] | ||
| Line 41: | Line 42: | ||
| - | '''<font color=# | + | '''<font color=#000000 font size=3>HIV covers its protein capsid with a viral envelop where GP160 is located. This glycoprotein facilitates fusion between the viral membrane and the host -cell membrane allowing liberation of the viral contents into the host cell. GP160 forms a trimer, where each monomer consists in two non-covalently associated subunits: a surface subunit GP120 that recognize and bind to specific receptor on the host cell and a transmembrane subunit GP41 that promotes membrane fusion.</font>''' |
[[Image:GIF-VIRUS-INFECTION1.gif|500px]] | [[Image:GIF-VIRUS-INFECTION1.gif|500px]] | ||
| Line 48: | Line 49: | ||
---- | ---- | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | '''<font color=#000000 font size=3>The images to the right show the self assembly of the HIV gp160 protein reconstituted into DOPC bilayer and adsorbed onto mica. Each pore is made up of 6 features with dimensions consistent with single molecules</font>''' | |
Current revision
_________ HIV gp160
|
|
| |
|
HIV covers its protein capsid with a viral envelop where GP160 is located. This glycoprotein facilitates fusion between the viral membrane and the host -cell membrane allowing liberation of the viral contents into the host cell. GP160 forms a trimer, where each monomer consists in two non-covalently associated subunits: a surface subunit GP120 that recognize and bind to specific receptor on the host cell and a transmembrane subunit GP41 that promotes membrane fusion.
The images to the right show the self assembly of the HIV gp160 protein reconstituted into DOPC bilayer and adsorbed onto mica. Each pore is made up of 6 features with dimensions consistent with single molecules |
