Freimoser

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<h3>[[Freimoser:Research|Research]]</h3>
<h3>[[Freimoser:Research|Research]]</h3>
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*Projects
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*Poly P
<h3>[[Freimoser:Publications|Publications]]</h3>
<h3>[[Freimoser:Publications|Publications]]</h3>
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<h3>[[Freimoser:Protocols|Protocols]]</h3>
<h3>[[Freimoser:Protocols|Protocols]]</h3>
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* [[Freimoser:Protocols:Yeast|Yeast]]<BR>
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* [[Freimoser:Protocols:Yeast|Yeast]]
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*Poly P
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*DNA
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*Protein
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<h3>[[Freimoser:Recipes|Recipes]]</h3>
<h3>[[Freimoser:Recipes|Recipes]]</h3>
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*Yeast media
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*Other media
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*Buffers (DNA)
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*Buffers (Proteins)
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<h3>[[Freimoser:Contact|Contact]]</h3>
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ETH Zurich<BR>
ETH Zurich<BR>
Institute of Plant Sciences<BR>
Institute of Plant Sciences<BR>

Revision as of 19:04, 5 October 2006


Research

  • Projects
  • Poly P

Publications

Protocols

  • Yeast
  • Poly P
  • DNA
  • Protein

Recipes

  • Yeast media
  • Other media
  • Buffers (DNA)
  • Buffers (Proteins)

Contact

ETH Zurich
Institute of Plant Sciences
Universitätsstr. 2
8092 Zürich
Switzerland

The molecule we study is so plain
the inorganic polyphosphate chain

The focus of the research in our group is a simple molecule: inorganic polyphosphate (poly P).
Poly P is a linear polymer that consists of a variable number of phosphate residues (from three to more than a thousand) that are linked by energy-rich phosphoanhydride bonds. It has been detected in all organisms and living cells and was found in many organelles. In eukaryotes, poly P is particularly prominent in fungi, algae and trypanosomatids. Poly P serves as a phosphate and energy store and regulates enzymes, chromatin condensation and translation. Poly P is also involved in bacterial pathogenicity, survival during stationary phase in bacteria and yeast, or the adaptation to alkaline and osmotic stress. In the slime mold Dictyostelium discoideum, poly P regulates development and predation behaviour, and in humans blood coagulation is accelerated and fibrinolysis is delayed by poly P. In our group we study poly P metabolism and functions in eukaryotes and we work mostly with yeast, filamentous fungi and algae.

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