Freimoser

From OpenWetWare

(Difference between revisions)
Jump to: navigation, search
Line 9: Line 9:
{| cellspacing="3"  
{| cellspacing="3"  
|- valign="top"
|- valign="top"
-
|width=800px align="justify"|
+
|width="100%" align="justify"|
<div style="clear: right; text-align: left; float: left; background-color: #ffff00; border: 5px; solid: #000000; padding: 3px 10px 3px 10px; margin: 12px 10px 0px 0px">
<div style="clear: right; text-align: left; float: left; background-color: #ffff00; border: 5px; solid: #000000; padding: 3px 10px 3px 10px; margin: 12px 10px 0px 0px">
<h3>The molecule we study is so plain<br>
<h3>The molecule we study is so plain<br>

Revision as of 15:35, 7 October 2006


The molecule we study is so plain
the inorganic polyphosphate chain

The focus of the research in our group is a simple molecule: inorganic polyphosphate (poly P).
Poly P is a linear polymer that consists of a variable number of phosphate residues (from three to more than a thousand) that are linked by energy-rich phosphoanhydride bonds. It has been detected in all organisms and living cells and was found in many organelles. In eukaryotes, poly P is particularly prominent in fungi, algae and trypanosomatids. Poly P serves as a phosphate and energy store and regulates enzymes, chromatin condensation and translation. Poly P is also involved in bacterial pathogenicity, survival during stationary phase in bacteria and yeast, or the adaptation to alkaline and osmotic stress. In the slime mold Dictyostelium discoideum, poly P regulates development and predation behaviour, and in humans blood coagulation is accelerated and fibrinolysis is delayed by poly P. In our group we study poly P metabolism and functions in eukaryotes and we work mostly with yeast, filamentous fungi and algae.

Personal tools