Freimoser

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linked by energy-rich phosphoanhydride bonds. It has been detected
linked by energy-rich phosphoanhydride bonds. It has been detected
in all organisms and living cells and was found in many organelles.
in all organisms and living cells and was found in many organelles.
-
In eukaryotes, poly P is particularly
+
Poly P also serves as a phosphate and energy store and regulates
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prominent in fungi, algae and trypanosomatids.
+
-
Poly P serves as a phosphate and energy store and regulates
+
enzymes, chromatin condensation
enzymes, chromatin condensation
-
and translation. Poly P is also involved in bacterial pathogenicity,
+
and translation. Poly P is involved in bacterial pathogenicity,
survival during stationary phase in
survival during stationary phase in
bacteria and yeast, or the adaptation to alkaline and osmotic stress.
bacteria and yeast, or the adaptation to alkaline and osmotic stress.
-
In the slime mold <i>Dictyostelium discoideum</i>, poly P regulates
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In <i>Dictyostelium discoideum</i>, poly P regulates
development and predation behaviour, and in humans blood coagulation is
development and predation behaviour, and in humans blood coagulation is
accelerated and fibrinolysis is delayed by poly P.
accelerated and fibrinolysis is delayed by poly P.
In our group we study poly P metabolism and functions in eukaryotes and
In our group we study poly P metabolism and functions in eukaryotes and
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we work mostly with yeast, filamentous fungi and algae.
+
we work mostly with yeast, filamentous fungi and algae. You are also welcome
 +
to visit our [http://www.polyphosphate.ethz.ch/ other web site].
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Revision as of 04:05, 10 October 2006


Florian M. Freimoser, PhD

Institute of Plant Sciences

Biochemistry and Physiology of Plants ETH Zurich, LFW D46.1
Universitätsstr. 2
CH-8092 Zurich
Switzerland
Tel: +41 +44 632 38 44
Fax: +41 +44 632 10 44

The molecule we study is so plain
the inorganic polyphosphate chain

The focus of the research in our group is a simple molecule: inorganic polyphosphate (poly P).
Poly P is a linear polymer that consists of a variable number of phosphate residues (from three to more than a thousand) that are linked by energy-rich phosphoanhydride bonds. It has been detected in all organisms and living cells and was found in many organelles. Poly P also serves as a phosphate and energy store and regulates enzymes, chromatin condensation and translation. Poly P is involved in bacterial pathogenicity, survival during stationary phase in bacteria and yeast, or the adaptation to alkaline and osmotic stress. In Dictyostelium discoideum, poly P regulates development and predation behaviour, and in humans blood coagulation is accelerated and fibrinolysis is delayed by poly P. In our group we study poly P metabolism and functions in eukaryotes and we work mostly with yeast, filamentous fungi and algae. You are also welcome

to visit our other web site.


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