Freimoser: Difference between revisions

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The molecule we study is so plain<br>
The molecule we study is so plain<br>
the inorganic polyphosphate chain
the inorganic polyphosphate chain

Revision as of 16:24, 4 October 2006

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Florian's Lab    People     Research     Publications     Protocols     Recipes     Links     Contact     Group info    

Technical

• Materials
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Contact Us

ETH Zurich
Institute of Plant Sciences
Universitätsstr. 2
8092 Zürich
Switzerland
Phone: 0041.(0)44.632'38'44

The molecule we study is so plain
the inorganic polyphosphate chain

The focus of the research in our group is a simple molecule: inorganic polyphosphate (poly P).
Poly P is a linear polymer that consists of a variable number of phosphate residues (from three to more than a thousand) that are linked by energy-rich phosphoanhydride bonds. It has been detected in all organisms and living cells and was found in many organelles. In eukaryotes, poly P is particularly prominent in fungi, algae and trypanosomatids. Poly P serves as a phosphate and energy store and regulates enzymes, chromatin condensation and translation. Poly P is also involved in bacterial pathogenicity, survival during stationary phase in bacteria and yeast, or the adaptation to alkaline and osmotic stress. In the slime mold Dictyostelium discoideum, poly P regulates development and predation behaviour, and in humans blood coagulation is accelerated and fibrinolysis is delayed by poly P. In our group we study poly P metabolism and functions in eukaryotes and we work mostly with yeast, filamentous fungi and algae. If you would like to learn more about our <a href="research.html">research</a> or our <a href="group.html">group</a> please visit our other pages. Or visit the website of the whole <a href="http://www.pbp.ipw.biol.ethz.ch/">group of Prof. Amrhein</a>, of which our lab is a part.

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