Gama:Research - Revision history

Margarida Gama-Carvalho at 18:27, 11 December 2012

Margarida Gama-Carvalho — Tue, 11 Dec 2012 18:27:15 GMT

←Older revision		Revision as of 18:27, 11 December 2012
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	==Research Information==		==Research Information==
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		+	The RNA biology and bioinformatics group focuses on the characterization and modeling of post-transcriptional regulatory networks involved in the coordination of gene expression programs in vertebrates, with a particular interest in regulatory events determined by the interaction of small non-coding RNAs and RNA binding proteins with mRNA untranslated sequence elements (UTRs). One main line of research investigates the role of 5' and 3' UTR elements in regulating gene expression. Our work focuses mainly on target mRNA molecules relevant for human development and disease. In particular, we are investigating mRNA regulatory mechanisms relevant for Spinal Muscular Atrophy, in an attempt to identify novel strategies for therapeutic intervention through the modulation of mRNA expression. We are also investigating how specific RNA binding proteins (U2AF, PTB1P, Quacking and Smn) act to coordinate gene expression programs relevant for vertebrate development and cell regulation. The use of bioinformatics for analysis of massive parallel sequencing data, sequence analysis, RNA structure and target prediction and modeling of gene-expression networks is central to our approaches.
		+	Another main line of research focuses on the role of microRNAs and other small non-coding RNAs in the control of gene expression. In particular, we are involved in a close collaborative project with the Clinical immunology and Retrovirology units of the Institute of Molecular Medicine to address the role of small non-coding RNAs during T-cell activation and in response to HIV infection.
		+

Margarida Gama-Carvalho: /* Research Information */

Margarida Gama-Carvalho — Wed, 27 Apr 2011 15:02:52 GMT

Research Information

←Older revision		Revision as of 15:02, 27 April 2011
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-	[[Gama:Projects \| ~~Information about ongoing~~ Projects]]	+	[[Gama:Projects \| Ongoing Projects]]

	[[Gama:Publications \| Group publications]]		[[Gama:Publications \| Group publications]]

	[[Gama:Links\| Interesting links]]		[[Gama:Links\| Interesting links]]

Margarida Gama-Carvalho: /* This page will have links to the following subpages */

Margarida Gama-Carvalho — Thu, 10 Mar 2011 13:41:53 GMT

This page will have links to the following subpages

←Older revision		Revision as of 13:41, 10 March 2011
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	==Research Information==		==Research Information==
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-	~~===This page will have links to the following subpages===~~

Margarida Gama-Carvalho at 16:52, 27 January 2011

Margarida Gama-Carvalho — Thu, 27 Jan 2011 16:52:56 GMT

←Older revision		Revision as of 16:52, 27 January 2011
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	{{Gama}}		{{Gama}}

-	~~[[Category:Lab]]~~

	<div style="padding: 10px; width: 720px; border: 2px solid #000000;">		<div style="padding: 10px; width: 720px; border: 2px solid #000000;">

Margarida Gama-Carvalho at 16:48, 27 January 2011

Margarida Gama-Carvalho — Thu, 27 Jan 2011 16:48:22 GMT

←Older revision		Revision as of 16:48, 27 January 2011
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		+	{{Gama}}
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		+	[[Category:Lab]]
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	<div style="padding: 10px; width: 720px; border: 2px solid #000000;">		<div style="padding: 10px; width: 720px; border: 2px solid #000000;">
		+
		+	==Research Information==

	===This page will have links to the following subpages===		===This page will have links to the following subpages===

Margarida Gama-Carvalho at 16:46, 27 January 2011

Margarida Gama-Carvalho — Thu, 27 Jan 2011 16:46:41 GMT

←Older revision		Revision as of 16:46, 27 January 2011
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-	Projects	+	<div style="padding: 10px; width: 720px; border: 2px solid #000000;">
-	Publications	+
-	Interesting links	+	===This page will have links to the following subpages===
		+
		+
		+	[[Gama:Projects \| Information about ongoing Projects]]
		+
		+	[[Gama:Publications \| Group publications]]
		+
		+	[[Gama:Links\| Interesting links]]

Margarida Gama-Carvalho: New page: Projects Publications Interesting links

Margarida Gama-Carvalho — Thu, 27 Jan 2011 16:37:26 GMT

New page: Projects Publications Interesting links

New page

Projects
Publications
Interesting links

←Older revision		Revision as of 15:02, 27 April 2011
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-	[[Gama:Projects \| ~~Information about ongoing~~ Projects]]	+	[[Gama:Projects \| Ongoing Projects]]

	[[Gama:Publications \| Group publications]]		[[Gama:Publications \| Group publications]]

	[[Gama:Links\| Interesting links]]		[[Gama:Links\| Interesting links]]