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==Contact Info==
==Contact Info==
[[Image:OWWEmblem.png|thumb|right|L. Richard-Parpaillon (an artistic interpretation)]]
[[Image:LaurentGiet.jpg|thumb|left|250 px]]
 
*Laurent Richard-Parpaillon
*Laurent Richard-Parpaillon
*UMR6061-CNRS. Institut de Génétique et Développement de Rennes.
*UMR6290-CNRS. Institut de Génétique et Développement de Rennes.
*Faculté de Médecine
*Faculté de Médecine
*2 avenue du Professeur Léon Bernard
*2 avenue du Professeur Léon Bernard
Line 11: Line 11:
*phone : 33 (0)2.23.23.44.72
*phone : 33 (0)2.23.23.44.72
*email : laurent.richard-parpaillon@univ-rennes1.fr
*email : laurent.richard-parpaillon@univ-rennes1.fr


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==Biography==
==Biography==
* Since 2010 : Member of Regis Giet group (Cytoskeleton and Cell Proliferation)
* 2003-2010 : Member of Jacek Kubiak group (Mitosis and meiosis)
* Since 2003 : Lecturer at the University of Rennes 1
* Since 2003 : Lecturer at the University of Rennes 1
* 2002-2003: Research associate at the Centre Européen des Sciences du Goût, CNRS, Dijon, France
* 2002-2003 : Research associate at the Centre Européen des Sciences du Goût, CNRS, Dijon, France
* 2000-2002: Research associate at the University of Cambridge (UK), Oncology department, Hutchison/MRC research center, "Cell division versus differentiation in the early embryo" group, Head : Dr.A. Philpott)
* 2000-2002 : Research associate at the University of Cambridge (UK), Oncology department, Hutchison/MRC research center, "Cell division versus differentiation in the early embryo" group, head : Dr.A. Philpott
* 1999 : PhD of Biology, University of Rennes 1, "Role of the IGF-1 receptor during Xenopus embryo development"  
* 1999       : PhD of Biology, University of Rennes 1, "Role of the IGF-1 receptor during Xenopus embryo development"  
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==Publications==
*Ensconsin/Map7 promotes microtubule growth and centrosome separation in Drosophila neural stem cells.
:Gallaud E, Caous R, Pascal A, Bazile F, Gagné JP, Huet S, Poirier GG, Chrétien D, '''Richard-Parpaillon L''', Giet R.
:J Cell Biol. 2014 Mar 31;204(7)[http://jcb.rupress.org/content/204/7/1111.long]
 
*Oocyte-somatic cells interactions, lessons from evolution.
:Charlier C, Montfort J, Chabrol O, Brisard D, Nguyen T, Cam A, '''Richard-Parpaillon L''', Moreews F, Pontarotti P, Uzbekova S, Chesnel F, Bobe J. BMC Genomics. 2012 Oct 19;13(1):560.


==Publications==
*Proteomics reveals a switch in CDK1-associated proteins upon M-phase exit during Xenopus laevis oocyte to embryo transition
*Proteomics reveals a switch in CDK1-associated proteins upon M-phase exit during Xenopus laevis oocyte to embryo transition
:Marteil G., Gagné JP, [[Richard-Parpaillon L.]], Borsuk E, Poirier G, Kubiak JZ. The International Journal of Biochemistry & Cell Biology (in press)
:Marteil G., Gagné JP, Borsuk E, '''Richard-Parpaillon L.''', Poirier G, Kubiak JZ. The International Journal of Biochemistry & Cell Biology. 2012 Jan;44(1):53-64.


*Proteomic screen for potential regulators of M-phase entry and quality of meiotic resumption in Xenopus laevis oocytes.
*Proteomic screen for potential regulators of M-phase entry and quality of meiotic resumption in Xenopus laevis oocytes.
:D'Inca R, Marteil G, Bazile F, Pascal A, Guitton N, Lavigne R, [[Richard-Parpaillon L]], Kubiak JZ. Journal of  Proteomics. 2010 Jun 16;73(8):1542-50.  
:D'Inca R, Marteil G, Bazile F, Pascal A, Guitton N, Lavigne R, R'''ichard-Parpaillon L''', Kubiak JZ. Journal of  Proteomics. 2010 Jun 16;73(8):1542-50.  


*EP45 accumulates in growing Xenopus laevis oocytes and has oocyte maturation enhancing activity.
*EP45 accumulates in growing Xenopus laevis oocytes and has oocyte maturation enhancing activity.
:Marteil G., D'Inca R., Pascal A., Guitton N., Midtun T., Anders G., [[Richard-Parpaillon L.]], Kubiak J.Z. Journal of Cell Sciences. 2010 May 15;123:1805-13  
:Marteil G., D'Inca R., Pascal A., Guitton N., Midtun T., Anders G., '''Richard-Parpaillon L.''', Kubiak J.Z. Journal of Cell Sciences. 2010 May 15;123:1805-13  


*Role of oocyte quality in meiotic maturation and embryonic development.
*Role of oocyte quality in meiotic maturation and embryonic development.
:Marteil G, [[Richard-Parpaillon L]], Kubiak JZ. Reproductive Biology. 2009 Nov;9(3):203-24.  
:Marteil G, '''Richard-Parpaillon L''', Kubiak JZ. Reproductive Biology. 2009 Nov;9(3):203-24.  


*Interaction of ZFPIP with PBX1 is crucial for proper expression of neural genetic markers during Xenopus development.
*Interaction of ZFPIP with PBX1 is crucial for proper expression of neural genetic markers during Xenopus development.
:Laurent A, Masse J, Deschamps S, Burel A, Omilli F, [[Richard-Parpaillon L]], Pellerin I. Development, Growth & Differentiation. 2009 Oct;51(8):699-706.  
:Laurent A, Masse J, Deschamps S, Burel A, Omilli F, '''Richard-Parpaillon L''', Pellerin I. Development, Growth & Differentiation. 2009 Oct;51(8):699-706.  


*ZFPIP/Zfp462 is maternally required for proper early Xenopus laevis development.
*ZFPIP/Zfp462 is maternally required for proper early Xenopus laevis development.
:Laurent A, Masse J, Omilli F, Deschamps S, [[Richard-Parpaillon L]], Chartrain I, Pellerin I. Developmental Biology. 2009 Mar 1;327(1):169-76.  
:Laurent A, Masse J, Omilli F, Deschamps S, '''Richard-Parpaillon L''', Chartrain I, Pellerin I. Developmental Biology. 2009 Mar 1;327(1):169-76.  


*Temporal regulation of embryonic M-phases.
*Temporal regulation of embryonic M-phases.
:Kubiak JZ, Bazile F, Pascal A, [[Richard-Parpaillon L]], Polanski Z, Ciemerych MA, Chesnel F. Folia Histochemica et Cytobiologica. 2008;46(1):5-9.  
:Kubiak JZ, Bazile F, Pascal A, '''Richard-Parpaillon L''', Polanski Z, Ciemerych MA, Chesnel F. Folia Histochemica et Cytobiologica. 2008;46(1):5-9.  


*Temporal regulation of the first mitosis in Xenopus and mouse embryos.
*Temporal regulation of the first mitosis in Xenopus and mouse embryos.
:Kubiak JZ, Chesnel F, [[Richard-Parpaillon L]], Bazile F, Pascal A, Polanski Z, Sikora-Polaczek M, Maciejewska Z, Ciemerych MA. Molecular and Cellular Endocrinology. 2008 Jan 30;282(1-2):63-9.  
:Kubiak JZ, Chesnel F, '''Richard-Parpaillon L''', Bazile F, Pascal A, Polanski Z, Sikora-Polaczek M, Maciejewska Z, Ciemerych MA. Molecular and Cellular Endocrinology. 2008 Jan 30;282(1-2):63-9.  


*Specific expression of olfactory binding protein in the aerial olfactory cavity of adult and developing Xenopus.
*Specific expression of olfactory binding protein in the aerial olfactory cavity of adult and developing Xenopus.
:Millery J, Briand L, Bézirard V, Blon F, Fenech C, [[Richard-Parpaillon L]], Quennedey B, Pernollet JC, Gascuel J. The European journal of neuroscience. 2005 Sep;22(6):1389-99.
:Millery J, Briand L, Bézirard V, Blon F, Fenech C, '''Richard-Parpaillon L''', Quennedey B, Pernollet JC, Gascuel J. The European journal of neuroscience. 2005 Sep;22(6):1389-99.


*Differences in regulation of the first two M-phases in Xenopus laevis embryo cell-free extracts.
*Differences in regulation of the first two M-phases in Xenopus laevis embryo cell-free extracts.
:Chesnel F, Vignaux F, [[Richard-Parpaillon L]], Huguet A, Kubiak JZ. Developmental Biology. 2005 Sep 15;285(2):358-75.
:Chesnel F, Vignaux F, '''Richard-Parpaillon L''', Huguet A, Kubiak JZ. Developmental Biology. 2005 Sep 15;285(2):358-75.


*Identification of Xenopus cyclin-dependent kinase inhibitors, p16Xic2 and p17Xic3.
*Identification of Xenopus cyclin-dependent kinase inhibitors, p16Xic2 and p17Xic3.
:Daniels M, Dhokia V, [[Richard-Parpaillon L]], Ohnuma S. Gene. 2004 Nov 10;342(1):41-7.
:Daniels M, Dhokia V, '''Richard-Parpaillon L''', Ohnuma S. Gene. 2004 Nov 10;342(1):41-7.


*G1/S phase cyclin-dependent kinase overexpression perturbs early development and delays tissue-specific differentiation in Xenopus.
*G1/S phase cyclin-dependent kinase overexpression perturbs early development and delays tissue-specific differentiation in Xenopus.
:[[Richard-Parpaillon L]], Cosgrove RA, Devine C, Vernon AE, Philpott A. Development. 2004 Jun;131(11):2577-86.  
:'''Richard-Parpaillon L''', Cosgrove RA, Devine C, Vernon AE, Philpott A. Development. 2004 Jun;131(11):2577-86.  


*Molecular cloning and characterization of an adaptor protein Shc isoform from Xenopus laevis oocytes.
*Molecular cloning and characterization of an adaptor protein Shc isoform from Xenopus laevis oocytes.
:Chesnel F, Heligon C, [[Richard-Parpaillon L]], Boujard D. Biology of the  Cell. 2003 Jul;95(5):311-20.
:Chesnel F, Heligon C, '''Richard-Parpaillon L''', Boujard D. Biology of the  Cell. 2003 Jul;95(5):311-20.


*The IGF pathway regulates head formation by inhibiting Wnt signaling in Xenopus.
*The IGF pathway regulates head formation by inhibiting Wnt signaling in Xenopus.
:[[Richard-Parpaillon L]], Héligon C, Chesnel F, Boujard D, Philpott A. Dev Biol. 2002 Apr 15;244(2):407-17.
:'''Richard-Parpaillon L''', Héligon C, Chesnel F, Boujard D, Philpott A. Dev Biol. 2002 Apr 15;244(2):407-17.


*Expression pattern of insulin receptor mRNA during Xenopus laevis embryogenesis.
*Expression pattern of insulin receptor mRNA during Xenopus laevis embryogenesis.
:[[Richard-Parpaillon L]] Groigno L, Boujard D. Mech Dev. 1999 Aug;86(1-2):151-4.
:'''Richard-Parpaillon L''' Groigno L, Boujard D. Mech Dev. 1999 Aug;86(1-2):151-4.


*The midbrain-hindbrain boundary genetic cascade is activated ectopically in the diencephalon in response to the widespread expression of one of its components, the medaka gene Ol-eng2.
*The midbrain-hindbrain boundary genetic cascade is activated ectopically in the diencephalon in response to the widespread expression of one of its components, the medaka gene Ol-eng2.
:Ristoratore F, Carl M, Deschet K, [[Richard-Parpaillon L]], Boujard D, Wittbrodt J, Chourrout D, Bourrat F, Joly JS. Development. 1999 Sep;126(17):3769-79.
:Ristoratore F, Carl M, Deschet K, '''Richard-Parpaillon L''', Boujard D, Wittbrodt J, Chourrout D, Bourrat F, Joly JS. Development. 1999 Sep;126(17):3769-79.


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Contact Info

  • Laurent Richard-Parpaillon
  • UMR6290-CNRS. Institut de Génétique et Développement de Rennes.
  • Faculté de Médecine
  • 2 avenue du Professeur Léon Bernard
  • 35043 RENNES Cedex
  • phone : 33 (0)2.23.23.44.72
  • email : laurent.richard-parpaillon@univ-rennes1.fr



Biography

  • Since 2003 : Lecturer at the University of Rennes 1
  • 2002-2003  : Research associate at the Centre Européen des Sciences du Goût, CNRS, Dijon, France
  • 2000-2002  : Research associate at the University of Cambridge (UK), Oncology department, Hutchison/MRC research center, "Cell division versus differentiation in the early embryo" group, head : Dr.A. Philpott
  • 1999  : PhD of Biology, University of Rennes 1, "Role of the IGF-1 receptor during Xenopus embryo development"


Publications

  • Ensconsin/Map7 promotes microtubule growth and centrosome separation in Drosophila neural stem cells.
Gallaud E, Caous R, Pascal A, Bazile F, Gagné JP, Huet S, Poirier GG, Chrétien D, Richard-Parpaillon L, Giet R.
J Cell Biol. 2014 Mar 31;204(7)[1]
  • Oocyte-somatic cells interactions, lessons from evolution.
Charlier C, Montfort J, Chabrol O, Brisard D, Nguyen T, Cam A, Richard-Parpaillon L, Moreews F, Pontarotti P, Uzbekova S, Chesnel F, Bobe J. BMC Genomics. 2012 Oct 19;13(1):560.
  • Proteomics reveals a switch in CDK1-associated proteins upon M-phase exit during Xenopus laevis oocyte to embryo transition
Marteil G., Gagné JP, Borsuk E, Richard-Parpaillon L., Poirier G, Kubiak JZ. The International Journal of Biochemistry & Cell Biology. 2012 Jan;44(1):53-64.
  • Proteomic screen for potential regulators of M-phase entry and quality of meiotic resumption in Xenopus laevis oocytes.
D'Inca R, Marteil G, Bazile F, Pascal A, Guitton N, Lavigne R, Richard-Parpaillon L, Kubiak JZ. Journal of Proteomics. 2010 Jun 16;73(8):1542-50.
  • EP45 accumulates in growing Xenopus laevis oocytes and has oocyte maturation enhancing activity.
Marteil G., D'Inca R., Pascal A., Guitton N., Midtun T., Anders G., Richard-Parpaillon L., Kubiak J.Z. Journal of Cell Sciences. 2010 May 15;123:1805-13
  • Role of oocyte quality in meiotic maturation and embryonic development.
Marteil G, Richard-Parpaillon L, Kubiak JZ. Reproductive Biology. 2009 Nov;9(3):203-24.
  • Interaction of ZFPIP with PBX1 is crucial for proper expression of neural genetic markers during Xenopus development.
Laurent A, Masse J, Deschamps S, Burel A, Omilli F, Richard-Parpaillon L, Pellerin I. Development, Growth & Differentiation. 2009 Oct;51(8):699-706.
  • ZFPIP/Zfp462 is maternally required for proper early Xenopus laevis development.
Laurent A, Masse J, Omilli F, Deschamps S, Richard-Parpaillon L, Chartrain I, Pellerin I. Developmental Biology. 2009 Mar 1;327(1):169-76.
  • Temporal regulation of embryonic M-phases.
Kubiak JZ, Bazile F, Pascal A, Richard-Parpaillon L, Polanski Z, Ciemerych MA, Chesnel F. Folia Histochemica et Cytobiologica. 2008;46(1):5-9.
  • Temporal regulation of the first mitosis in Xenopus and mouse embryos.
Kubiak JZ, Chesnel F, Richard-Parpaillon L, Bazile F, Pascal A, Polanski Z, Sikora-Polaczek M, Maciejewska Z, Ciemerych MA. Molecular and Cellular Endocrinology. 2008 Jan 30;282(1-2):63-9.
  • Specific expression of olfactory binding protein in the aerial olfactory cavity of adult and developing Xenopus.
Millery J, Briand L, Bézirard V, Blon F, Fenech C, Richard-Parpaillon L, Quennedey B, Pernollet JC, Gascuel J. The European journal of neuroscience. 2005 Sep;22(6):1389-99.
  • Differences in regulation of the first two M-phases in Xenopus laevis embryo cell-free extracts.
Chesnel F, Vignaux F, Richard-Parpaillon L, Huguet A, Kubiak JZ. Developmental Biology. 2005 Sep 15;285(2):358-75.
  • Identification of Xenopus cyclin-dependent kinase inhibitors, p16Xic2 and p17Xic3.
Daniels M, Dhokia V, Richard-Parpaillon L, Ohnuma S. Gene. 2004 Nov 10;342(1):41-7.
  • G1/S phase cyclin-dependent kinase overexpression perturbs early development and delays tissue-specific differentiation in Xenopus.
Richard-Parpaillon L, Cosgrove RA, Devine C, Vernon AE, Philpott A. Development. 2004 Jun;131(11):2577-86.
  • Molecular cloning and characterization of an adaptor protein Shc isoform from Xenopus laevis oocytes.
Chesnel F, Heligon C, Richard-Parpaillon L, Boujard D. Biology of the Cell. 2003 Jul;95(5):311-20.
  • The IGF pathway regulates head formation by inhibiting Wnt signaling in Xenopus.
Richard-Parpaillon L, Héligon C, Chesnel F, Boujard D, Philpott A. Dev Biol. 2002 Apr 15;244(2):407-17.
  • Expression pattern of insulin receptor mRNA during Xenopus laevis embryogenesis.
Richard-Parpaillon L Groigno L, Boujard D. Mech Dev. 1999 Aug;86(1-2):151-4.
  • The midbrain-hindbrain boundary genetic cascade is activated ectopically in the diencephalon in response to the widespread expression of one of its components, the medaka gene Ol-eng2.
Ristoratore F, Carl M, Deschet K, Richard-Parpaillon L, Boujard D, Wittbrodt J, Chourrout D, Bourrat F, Joly JS. Development. 1999 Sep;126(17):3769-79.

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