Guillaume Lesage: Difference between revisions

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==Contact Info==
==Contact Info==
[[Image:Hung_Viet_Trinh.JPG|200px|right]]
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*Guillaume Lesage
*Guillaume Lesage
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==Current position==
==Current position==
PhD Student in the Hemmi Lab (University of Zurich)<br/>
PhD Student in the [http://www.molbio.uzh.ch/groups/hemmi/index.shtml Hemmi Lab], [http://www.molbio.uzh.ch/ Institute of Molecular Biology], [http://www.uzh.ch/index_en.html University of Zurich]<br/>
Projects:
Projects:
*Engineering of Oncolytic CRAds for Melanoma Treatment
*Engineering of Oncolytic CRAds for Melanoma Treatment
*Study on Potential miRNAs Encoded by Human Adenoviruses<br/>
*Study on Potential miRNAs Encoded by Human Adenoviruses<br/>
Founding member of the MicroRNA Network Zurich ([[MiNZ]]).


==Previous labs==
==Previous labs==
*Dec 2004 - Feb 2006: [http://www.fussenegger.ethz.ch/ Fussenegger Lab], [http://www.ethz.ch/index_EN ETH Zurich], Switzerland<br/>
Supervisors: Dr. J. Stitz, Prof. M. Fussenegger<br/>
Projects: Light-inducible gene regulation system / Engineering and pseudotyping of the Duck Hepatitis B Virus (DHBV)<br/>
*Oct 2003 - Jul 2004: [http://www.neb.com New England Biolabs, Inc.], Beverly, MA, USA
Supervisor: Dr. M.-Q. Xu<br/>
Project: Protein transduction assays on eukaryotic cells
*Jan - Sep 2003: [http://www.neb.com New England Biolabs, Inc.], Beverly, MA, USA
Supervisor: Dr. M.-Q. Xu<br/>
Projects: Mutagenesis study of the Ssp DnaB mini-intein / Catalytic RNA in RNAi production


==Education==
==Education==
*'''Master Degree of Science in Biotechnology''', September 2003, Strasbourg, France
*Master Degree of Science in Biotechnology / Diplôme d’ingénieur en Biotechnologie / Diplôme d’Etude Approfondie (DEA) in Cellular and Molecular Biology
**''Diplôme d’ingénieur en Biotechnologie''<br/>
[http://www-esbs.u-strasbg.fr/ Ecole supérieure de Biotechnologie de Strasbourg (ESBS)] (graduated September 2003 in Strasbourg, France)<br/>
''Diplôme d’Etude Approfondie (DEA) in Cellular and Molecular Biology<br/>''
''Tri-lingual (French, English and German) Biotechnology Masters program emphasizing practical laboratory training''
Ecole supérieure de Biotechnologie de Strasbourg (ESBS):<br/>
*Diplôme d'études universitaires générales (DEUG) in Biology
Tri-lingual (French, English and German) Biotechnology Masters program emphasizing practical laboratory training.
Institut d'Ecologie Appliquée, [http://www.uco.fr/index.jsp#1 Université catholique de l'Ouest] (graduated August 2000 in Angers, France)
*'''Diplôme d'études universitaires générales (DEUG) in Biology''', August 2000, Angers, France'''
Institut d'Ecologie Appliquée, Université catholique de l'Ouest.


==Publications==
==Publications==
<biblio>
#Paper3 pmid=18776931
#Paper2 pmid=17461419
#Paper1 pmid=12878593
</biblio>
==Activities==
*Former active member of the Swiss country board of [http://www.yebn.org YEBN (Young European Biotech Network)]: Part of the organizing team of the annual meeting 2004 in Zurich and part of the sponsor recruiting team from February 2005 to February 2006<br/>
*Active participation in the [http://www-esbs.u-strasbg.fr ESBS] Alumni Day 2005<br/>
*Founding member of the MicroRNA Network Zurich ([[MiNZ]])


==Useful links==
==Useful links==
[http://www-esbs.u-strasbg.fr Ecole Sperieure de Biotechnologie de Strasbourg (ESBS)]<br/>
[http://www.molbio.uzh.ch Institute of Molecular Biology]<br/>
[http://http://www.lszgs.ch/index.php?id=17 Zurich Ph.D. Program in Molecular Life Sciences]<br/>
[http://www.neb.com New England Biolabs, Inc.]<br/>
[http://www.yebn.org Young European Biotech Network]

Latest revision as of 06:17, 15 October 2008

Contact Info

  • Guillaume Lesage
  • University of Zurich

     Institute of Molecular Biology / Hemmi Lab
     Winterthurerstrasse 190
     8057 Zurich
     Switzerland

Research interests

  • Virology
  • MicroRNAs

Current position

PhD Student in the Hemmi Lab, Institute of Molecular Biology, University of Zurich
Projects:

  • Engineering of Oncolytic CRAds for Melanoma Treatment
  • Study on Potential miRNAs Encoded by Human Adenoviruses

Previous labs

Supervisors: Dr. J. Stitz, Prof. M. Fussenegger
Projects: Light-inducible gene regulation system / Engineering and pseudotyping of the Duck Hepatitis B Virus (DHBV)

Supervisor: Dr. M.-Q. Xu
Project: Protein transduction assays on eukaryotic cells

Supervisor: Dr. M.-Q. Xu
Projects: Mutagenesis study of the Ssp DnaB mini-intein / Catalytic RNA in RNAi production

Education

  • Master Degree of Science in Biotechnology / Diplôme d’ingénieur en Biotechnologie / Diplôme d’Etude Approfondie (DEA) in Cellular and Molecular Biology

Ecole supérieure de Biotechnologie de Strasbourg (ESBS) (graduated September 2003 in Strasbourg, France)
Tri-lingual (French, English and German) Biotechnology Masters program emphasizing practical laboratory training

  • Diplôme d'études universitaires générales (DEUG) in Biology

Institut d'Ecologie Appliquée, Université catholique de l'Ouest (graduated August 2000 in Angers, France)

Publications

  1. Galgano A, Forrer M, Jaskiewicz L, Kanitz A, Zavolan M, and Gerber AP. Comparative analysis of mRNA targets for human PUF-family proteins suggests extensive interaction with the miRNA regulatory system. PLoS One. 2008 Sep 8;3(9):e3164. DOI:10.1371/journal.pone.0003164 | PubMed ID:18776931 | HubMed [Paper3]
  2. Fluri DA, Kelm JM, Lesage G, Baba MD, and Fussenegger M. InXy and SeXy, compact heterologous reporter proteins for mammalian cells. Biotechnol Bioeng. 2007 Oct 15;98(3):655-67. DOI:10.1002/bit.21461 | PubMed ID:17461419 | HubMed [Paper2]
  3. Ding Y, Xu MQ, Ghosh I, Chen X, Ferrandon S, Lesage G, and Rao Z. Crystal structure of a mini-intein reveals a conserved catalytic module involved in side chain cyclization of asparagine during protein splicing. J Biol Chem. 2003 Oct 3;278(40):39133-42. DOI:10.1074/jbc.M306197200 | PubMed ID:12878593 | HubMed [Paper1]

All Medline abstracts: PubMed | HubMed

Activities

  • Former active member of the Swiss country board of YEBN (Young European Biotech Network): Part of the organizing team of the annual meeting 2004 in Zurich and part of the sponsor recruiting team from February 2005 to February 2006
  • Active participation in the ESBS Alumni Day 2005
  • Founding member of the MicroRNA Network Zurich (MiNZ)

Useful links

Ecole Sperieure de Biotechnologie de Strasbourg (ESBS)
Institute of Molecular Biology
Zurich Ph.D. Program in Molecular Life Sciences
New England Biolabs, Inc.
Young European Biotech Network