Guillaume Lesage
Contact Info
- Guillaume Lesage
- University of Zurich
Institute of Molecular Biology / Hemmi Lab
Winterthurerstrasse 190
8057 Zurich
Switzerland
- Contact me here: guillaume.lesage@molbio.uzh.ch
Research interests
- Virology
- MicroRNAs
Current position
PhD Student in the Hemmi Lab, Institute of Molecular Biology, University of Zurich
Projects:
- Engineering of Oncolytic CRAds for Melanoma Treatment
- Study on Potential miRNAs Encoded by Human Adenoviruses
Founding member of the MicroRNA Network Zurich (MiNZ).
Previous labs
Previous labs
- Dec 2004 - Feb 2006: Fussenegger Lab, ETH Zurich, Switzerland
Supervisors: Dr. J. Stitz, Prof. M. Fussenegger
Projects: Light-inducible gene regulation system / Engineering and pseudotyping of the Duck Hepatitis B Virus (DHBV)
- Oct 2003 - Jul 2004: New England Biolabs, Inc., Beverly, MA, USA
Supervisor: Dr. M.-Q. Xu
Project: Protein transduction assays on eukaryotic cells
- Jan - Sep 2003: New England Biolabs, Inc., Beverly, MA, USA
Supervisor: Dr. M.-Q. Xu
Projects: Mutagenesis study of the Ssp DnaB mini-intein / Catalytic RNA in RNAi production
Education
- Master Degree of Science in Biotechnology
- Diplôme d’ingénieur en Biotechnologie
- Diplôme d’Etude Approfondie (DEA) in Cellular and Molecular Biology
Ecole supérieure de Biotechnologie de Strasbourg (ESBS) (graduated September 2003 in Strasbourg, France)
Tri-lingual (French, English and German) Biotechnology Masters program emphasizing practical laboratory training
- Diplôme d'études universitaires générales (DEUG) in Biology
Institut d'Ecologie Appliquée, Université catholique de l'Ouest (graduated August 2000 in Angers, France)
Publications
- Galgano A, Forrer M, Jaskiewicz L, Kanitz A, Zavolan M, and Gerber AP. Comparative analysis of mRNA targets for human PUF-family proteins suggests extensive interaction with the miRNA regulatory system. PLoS One. 2008 Sep 8;3(9):e3164. DOI:10.1371/journal.pone.0003164 |
- Fluri DA, Kelm JM, Lesage G, Baba MD, and Fussenegger M. InXy and SeXy, compact heterologous reporter proteins for mammalian cells. Biotechnol Bioeng. 2007 Oct 15;98(3):655-67. DOI:10.1002/bit.21461 |
- Ding Y, Xu MQ, Ghosh I, Chen X, Ferrandon S, Lesage G, and Rao Z. Crystal structure of a mini-intein reveals a conserved catalytic module involved in side chain cyclization of asparagine during protein splicing. J Biol Chem. 2003 Oct 3;278(40):39133-42. DOI:10.1074/jbc.M306197200 |
