Gunawan:Ang Kok Siong: Difference between revisions
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==[[Special:Emailuser/Ang, Kok Siong|Ang, Kok Siong]]== | ==[[Special:Emailuser/Ang, Kok Siong|Ang, Kok Siong]]== | ||
[[Image:Kok Siong lab crop.JPG|250px|right|Ang Kok Siong]] | [[Image:Kok Siong lab crop.JPG|250px|right|Ang Kok Siong]] | ||
4 Engineering Drive 4 Block E5 #B-05 <BR> | |||
4 Engineering Drive 4 | National University of Singapore <BR> | ||
Singapore 117576 <BR> | |||
Singapore 117576 < | |||
Tel:+65 6516 7859 | Tel:+65 6516 7859 | ||
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==Education== | ==Education== | ||
<!--Include info about your educational background--> | <!--Include info about your educational background--> | ||
* | * 2006, B.Eng (Chem), National University of Singapore, Singapore. | ||
==Research interests== | ==Research interests== | ||
<!-- Feel free to add brief descriptions to your research interests as well --> | <!-- Feel free to add brief descriptions to your research interests as well --> | ||
;Parameter Estimation of Oscillatory Systems | |||
:<p align='justify'>Oscillatory behavior is exhibited by many biological systems. Examples these include the circadian rhythm and p53-mdm2 response to DNA damage. Such dynamical behavior is important and integral of a higher biological function, such as sleeping and feeding patterns (circadian rhythm) and DNA repair (p53-mdm2). To study these systems, in-silico models have been developed to aid in the analysis. However, the corresponding model parameters are usually chosen qualitatively such that the system to exhibit the general characteristics of experimental data. The focus of the research here is to facilitate reconciliation of the model with experimental data in a quantitative manner.</p> | |||
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Oscillatory behavior is exhibited by many biological systems. Examples these include the circadian rhythm and p53-mdm2 response to DNA damage. Such dynamical behavior is important and integral of a higher biological function, such as sleeping and feeding patterns (circadian rhythm) and DNA repair (p53-mdm2). To study these systems, in-silico models have been developed to aid in the analysis. However, the corresponding model parameters are usually chosen qualitatively such that the system to exhibit the general characteristics of experimental data. The focus of the research here is to facilitate reconciliation of the model with experimental data in a quantitative manner. | |||
==Publications== | ==Publications== | ||
<!-- Replace the PubMed ID's ("pmid=#######") below with the PubMed ID's for your publications. You can add or remove lines as needed, #Paper1 pmid=6947258, #Book1 isbn=0879697164 // leave a comment about a paper here --> | <!-- Replace the PubMed ID's ("pmid=#######") below with the PubMed ID's for your publications. You can add or remove lines as needed, #Paper1 pmid=6947258, #Book1 isbn=0879697164 // leave a comment about a paper here --> | ||
==Useful links== | ==Useful links== | ||
*[ | *[http://Gunawan.openwetware.org/ Our Lab webpage] | ||
Revision as of 05:15, 31 July 2008
Chemical and Biological Systems Engineering Laboratory
Ang, Kok Siong
4 Engineering Drive 4 Block E5 #B-05
National University of Singapore
Singapore 117576
Tel:+65 6516 7859
I work in the Gunawan Lab at National University of Singapore.
Education
- 2006, B.Eng (Chem), National University of Singapore, Singapore.
Research interests
- Parameter Estimation of Oscillatory Systems
Oscillatory behavior is exhibited by many biological systems. Examples these include the circadian rhythm and p53-mdm2 response to DNA damage. Such dynamical behavior is important and integral of a higher biological function, such as sleeping and feeding patterns (circadian rhythm) and DNA repair (p53-mdm2). To study these systems, in-silico models have been developed to aid in the analysis. However, the corresponding model parameters are usually chosen qualitatively such that the system to exhibit the general characteristics of experimental data. The focus of the research here is to facilitate reconciliation of the model with experimental data in a quantitative manner.
