Gunawan:Jia Gengjie: Difference between revisions

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==Journal Publications==
==Journal Publications==
G. Jia and R. Gunawan. Parameter estimation of kinetic models from metabolic profiles:two-phase dynamic decoupling method. Bioinformatics., 27 (14) 1964-1970
*G. Jia and R. Gunawan. Parameter estimation of kinetic models from metabolic profiles:two-phase dynamic decoupling method. Bioinformatics., 27 (14) 1964-1970


==Peer reviewed Conference Proceedings==
==Peer reviewed Conference Proceedings==

Latest revision as of 08:39, 5 July 2011

Chemical and Biological Systems Engineering Laboratory

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Jia Gengjie

Jia Gengjie
Jia Gengjie

Department of Chemical and Biomolecular Engineering
4 Engineering Drive 4 Block E5 #B-05
National University of Singapore
Singapore 117576
Tel:+65 6516 7859

I work in the Gunawan lab at National University of Singapore.

Education

  • 2008, B.Sc(Bioscience), University of Science and Technology of China.

Research Interests

Metabolic Model Identification Parameter Estimation and Structure Identification

  • Parameter estimation of kinetic models from incomplete metabolic profiles

In order to meet the challenges arising by incomplete and noisy data, a combined iterative approach is proposed to estimate the parameters and fill the missing information.

  • Parameter estimation of kinetic models - How to use stationary data for dynamics

In order to maximize the information behind data, the stationary part and dynamic part of time series data are separated and play different roles in the parameter estimation.

  • Structure identification of kinetic models - An incremental strategy

For the future work, an incremental strategy will be developed to identify kinetic models including network stoichiometry and kinetic parameters from time series data.

Optimal control of crystallization processes

Journal Publications

  • G. Jia and R. Gunawan. Parameter estimation of kinetic models from metabolic profiles:two-phase dynamic decoupling method. Bioinformatics., 27 (14) 1964-1970

Peer reviewed Conference Proceedings

  • Gengjie J, Gunawan R. (2010) Parameter Estimation of Kinetic Models from Incomplete Metabolic Profiles, In 11th International Conference on Systems Biology, Edinburgh, UK, Oct 11-15 (poster).
  • Gengjie J, Gunawan R. (2010) Parameter Estimation of Kinetic Models from Incomplete Metabolic Profiles, In 5th International Symposium on Design, Operation and Control of Chemical Processes (PSE Asia), Singapore, July 25-28


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