Hartman Behavioral Neuroscience Lab: Difference between revisions
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Our lab at [[Loma Linda University]] in [http://maps.google.com/maps?f=q&hl=en&geocode=&q=loma+linda,+ca&ie=UTF8&t=h&ll=35.245619,-117.246094&spn=8.268015,17.86377&z=6&iwloc=addr southern California] primarily uses animal models to understand the biological basis of learning/memory and how aging, brain injury or disease can alter behavior. Techniques used include behavioral assessment (e.g., [[Hartman Behavioral Neuroscience Lab: | Our lab at [[Loma Linda University]] in [http://maps.google.com/maps?f=q&hl=en&geocode=&q=loma+linda,+ca&ie=UTF8&t=h&ll=35.245619,-117.246094&spn=8.268015,17.86377&z=6&iwloc=addr southern California] primarily uses animal models to understand the biological basis of learning/memory and how aging, brain injury or disease can alter behavior. Techniques used include behavioral assessment (e.g., [[Hartman Behavioral Neuroscience Lab:Protocols#water maze |water maze]]) of rats and genetically modified ([http://en.wikipedia.org/wiki/Transgenic transgenic] / [http://en.wikipedia.org/wiki/Knockout_%28genetics%29 knockout]) mice, pharmacology (e.g., manipulation of behavior with various drugs), small animal surgery (e.g., intracardial perfusion, electrolytic brain lesions, induction of ischemic stroke), [http://en.wikipedia.org/wiki/Histology histology] / [http://en.wikipedia.org/wiki/Immunohistochemistry immunohistochemistry] (e.g., visualization of amyloid plaques in brain slices), [http://en.wikipedia.org/wiki/Stereology stereological] microscopy (unbiased quantification of brain structures under a microscope), and [http://en.wikipedia.org/wiki/Biochemistry biochemistry] (e.g., protein assays of brain tissue using [http://en.wikipedia.org/wiki/Western_blot Western blot] and [http://en.wikipedia.org/wiki/ELISA ELISA]). | ||
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Revision as of 14:52, 4 November 2008
Our lab at Loma Linda University in southern California primarily uses animal models to understand the biological basis of learning/memory and how aging, brain injury or disease can alter behavior. Techniques used include behavioral assessment (e.g., water maze) of rats and genetically modified (transgenic / knockout) mice, pharmacology (e.g., manipulation of behavior with various drugs), small animal surgery (e.g., intracardial perfusion, electrolytic brain lesions, induction of ischemic stroke), histology / immunohistochemistry (e.g., visualization of amyloid plaques in brain slices), stereological microscopy (unbiased quantification of brain structures under a microscope), and biochemistry (e.g., protein assays of brain tissue using Western blot and ELISA).
