Harvard:Biophysics 101/2007/04/10

What we have now:

• Sequence
• RS#
• OMIM
• Parsed OMIM output
  • Pubmed - reviews and related articles
  • News (sort good from bad)
  • Wikipedia

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What we need:

• Prioritize RS# - How to quantify the criteria below?
  • Disease relevance
    • Number of PMID's
    • Number of drugs for particular disease
    • Disease lists from WHO - cross ref with pubmed
  • Frequency of deleterious allele
    • GeneCards
  • Clustering alleles for relevance to particular diseases
  • Treatment
    • Emedicine
  • Known alleles
  • Penetrance
• Web interface
  • Not just script also paste in sequence
  • Maybe useful source for getting sequence data
• Non OMIM based analysis of sequences