Harvard:Biophysics 101/2007/04/10: Difference between revisions

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What we have now:
==What we have now==


*Sequence
*Sequence
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**Wikipedia
**Wikipedia


What we need:  
==What we need==
*I added the names of those who signed up in class -[[User:Cchi|Cchi]] 19:00, 11 April 2007 (EDT)
<pre>
Please sign up for problems below
</pre>


*Prioritize RS# - How to quantify the criteria below?
*Prioritize RS# - How to quantify the criteria below?
**Disease relevance - Number of PMID's
**Disease relevance  
**Frequency
***Number of PMID's
**Treatment - [[http://www.emedicine.com/ Emedicine]]
***Number of drugs for particular disease
***Disease lists from WHO - cross ref with pubmed
***CDC
***Keywords in disease classification
****Mesh terms - Deniz
****Keywords from OMIM - Resmi
***California excel table - frequency of diagnosis - Zach
***Clustering algorithm (on the side) - Kay
**Frequency of deleterious allele
***[http://www.genecards.org/index.shtml GeneCards]
***Clustering alleles with respect to genes and particular diseases
**Treatment
***[http://www.emedicine.com/ Emedicine] - Tiff
***Known drugs, devices, patents, total dolars spent
***WHO - Hetmann and Cynthia
****Curable
****Treatable
****Preventable
**Known alleles
**Known alleles
**Penetrance
**Penetrance
***WIKI brainstorm - HapMap?? OMIM?
*Web interface
*Web interface
**Not just script also paste in sequence
**Not just script also paste in sequence - Xiaodi
**Maybe useful source for getting sequence data
**Maybe useful source for getting sequence data
*Non OMIM based analysis of sequences - Chris
**SNPdb?
*Presentation of Information
**Review articles
***use PMID's for related review articles - Resmi
***Beyond PubMed: Google scholar
**News
***Beyond Google News, restricting to certain sites
**Social Network?

Latest revision as of 13:30, 14 April 2007

What we have now

  • Sequence
  • RS#
  • OMIM
  • Parsed OMIM output
    • Pubmed - reviews and related articles
    • News (sort good from bad)
    • Wikipedia

What we need

  • I added the names of those who signed up in class -Cchi 19:00, 11 April 2007 (EDT)
Please sign up for problems below
  • Prioritize RS# - How to quantify the criteria below?
    • Disease relevance
      • Number of PMID's
      • Number of drugs for particular disease
      • Disease lists from WHO - cross ref with pubmed
      • CDC
      • Keywords in disease classification
        • Mesh terms - Deniz
        • Keywords from OMIM - Resmi
      • California excel table - frequency of diagnosis - Zach
      • Clustering algorithm (on the side) - Kay
    • Frequency of deleterious allele
      • GeneCards
      • Clustering alleles with respect to genes and particular diseases
    • Treatment
      • Emedicine - Tiff
      • Known drugs, devices, patents, total dolars spent
      • WHO - Hetmann and Cynthia
        • Curable
        • Treatable
        • Preventable
    • Known alleles
    • Penetrance
      • WIKI brainstorm - HapMap?? OMIM?
  • Web interface
    • Not just script also paste in sequence - Xiaodi
    • Maybe useful source for getting sequence data
  • Non OMIM based analysis of sequences - Chris
    • SNPdb?
  • Presentation of Information
    • Review articles
      • use PMID's for related review articles - Resmi
      • Beyond PubMed: Google scholar
    • News
      • Beyond Google News, restricting to certain sites
    • Social Network?