Harvard:Biophysics 101/2007/04/10

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(What we need)
(What we need)
Line 33: Line 33:
**Known alleles
**Known alleles
**Penetrance
**Penetrance
-
***WIKI brainstorm
+
***WIKI brainstorm - HapMap??
*Web interface
*Web interface
**Not just script also paste in sequence
**Not just script also paste in sequence

Revision as of 11:30, 10 April 2007

What we have now

  • Sequence
  • RS#
  • OMIM
  • Parsed OMIM output
    • Pubmed - reviews and related articles
    • News (sort good from bad)
    • Wikipedia

What we need

Please sign up for problems below
  • Prioritize RS# - How to quantify the criteria below?
    • Disease relevance
      • Number of PMID's
      • Number of drugs for particular disease
      • Disease lists from WHO - cross ref with pubmed
      • CDC
      • California excel table - frequency of diagnosis
    • Frequency of deleterious allele
    • Clustering alleles with respect to genes and particular diseases
    • Treatment
      • Emedicine
      • Known drugs, devices, patents, total dolars spent
      • WHO
        • Curable
        • Treatable
        • Preventable
    • Known alleles
    • Penetrance
      • WIKI brainstorm - HapMap??
  • Web interface
    • Not just script also paste in sequence
    • Maybe useful source for getting sequence data
  • Non OMIM based analysis of sequences

Resources for disease frequency

--Zsun

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