Haynes:LitRviewMar2012

Spring 2012, 3/30/12

ACS Synthetic Biology

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FEBS Letters

1. Kono H, Imanishi M, Negi S, Tatsutani K, Sakaeda Y, et al. (2012). Rational design of DNA sequence-specific zinc fingers. FEBS letters. 586: 918–923.
Summary: Sugiura's group from Kyoto, Japan mutated zinc finger DNA binding domains to increase binding affinity.

Frontiers in Microbiotechnology

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Journal of Biological Engineering

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Journal of Cell Biology

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Molecular Biology of the Cell

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Molecular and Cellular Biology

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Nature

1. Dana GV, Kuiken T, Rejeski D, Snow A. (2012). Four steps to avoid a synthetic-biology disaster. Nature. 483: 29.
Summary: A group from the Synthetic Biology project at the Woodrow Wilson Institute (http://www.synbioproject.org/) suggests four key areas for testing and determining the safety of synthetic organisms.

Nature Biotechnology

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PLoS Biology

1. Levine JH, Fontes ME., Dworkin J, Elowitz, MB (2012). Pulsed feedback defers cellular differentiation. PLoS Biology, 10(1), e1001252. doi:10.1371/journal.pbio.1001252
Summary: The Elowitz lab from Cal Tech reports a mechanism underlying a biological timer in bacteria (Bacillus subtilis).

2. Nishida, K., & Silver, P. A. (2012). Induction of biogenic magnetization and redox control by a component of the target of rapamycin complex 1 signaling pathway. PLoS Biology. 10(2), e1001269. doi:10.1371/journal.pbio.1001269
Summary: The Silver lab from Harvard reports genetic manipulation of yeast to make it accumulate more magnetic iron (Fe3+) and display enhanced magnetic properties. There's a very good blog article on this project at the Scientific American: http://blogs.scientificamerican.com/oscillator/2012/02/28/magnetic-yeast/

Systems and Synthetic Biology

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