Our group uses synthetic, systems, and quantitative biology to engineer useful gene and protein-based biological devices and to deepen our understanding of molecular cell biology. We operate biological devices primarily in human/ mammalian cells. Accelerating the pace of therapeutic technologies (such as tissue regeneration and customizable protein-based drugs) via modular design is the grand challenge that shapes our research plans.
- Synthetic chromatin for human cell differentiation - Behzad Damadzadeh
- Microbial communication with synthetic quorum sensing - Rene Davis
- Engineering epigenetic transcription factors - Brady Laughlin (FURI)
- Protein-DNA fusions in living microbes - Ryan Muller (SOLUR)
- Synthetic chromatin and UV-damage - Brendan Fries (SOLUR)