Haynes Lab:Notebook/Synthetic Biology and Bioinformatics for Predictable Control of Therapeutic Gene2 - Revision history

Caroline Hom: /* Notes */

Caroline Hom — Wed, 17 Apr 2013 01:55:45 GMT

Notes

←Older revision		Revision as of 01:55, 17 April 2013
Line 17:		Line 17:

	==Notes==		==Notes==
-	* Phase 3 is ~~complete~~	+	* Phase 3 is in progress

Caroline Hom: /* Notes */

Caroline Hom — Wed, 17 Apr 2013 01:55:35 GMT

Notes

←Older revision		Revision as of 01:55, 17 April 2013
Line 17:		Line 17:

	==Notes==		==Notes==
-	* Phase 2 is complete	+	* Phase 3 is complete

Caroline Hom: /* Notes */

Caroline Hom — Wed, 17 Apr 2013 01:55:18 GMT

Notes

←Older revision		Revision as of 01:55, 17 April 2013
Line 17:		Line 17:

	==Notes==		==Notes==
-	* Phase ~~3 in progress~~	+	* Phase 2 is complete

Caroline Hom: /* Notes */

Caroline Hom — Wed, 17 Apr 2013 01:54:41 GMT

Notes

←Older revision		Revision as of 01:54, 17 April 2013
Line 17:		Line 17:

	==Notes==		==Notes==
-	* Phase 2 in progress	+	* Phase 3 in progress

Caroline Hom: /* Project Description/Abstract */

Caroline Hom — Wed, 17 Apr 2013 01:54:29 GMT

Project Description/Abstract

←Older revision		Revision as of 01:54, 17 April 2013
Line 13:		Line 13:
	\|-		\|-
	\|colspan="2"\|		\|colspan="2"\|
-	==~~Project Description/Abstract~~==	+	==Phase 3: Expression==
-	*	+	At this stage the necessary bioinformatics has been performed in order to identify which genes could be potentially turned on by PcTF. Using Real-Time qRT-PCR we can determine which genes form that list are up-regulated and what further analysis need to be performed. We will also continue research by seeing how cell phenotype and growth are affected by PcTF.

	==Notes==		==Notes==

Caroline Hom: /* Project Description/Abstract */

Caroline Hom — Mon, 18 Jun 2012 21:03:10 GMT

Project Description/Abstract

←Older revision		Revision as of 21:03, 18 June 2012
Line 14:		Line 14:
	\|colspan="2"\|		\|colspan="2"\|
	==Project Description/Abstract==		==Project Description/Abstract==
-	* Since a comprehensive ChIP map is not available for osteosarcoma, I will identify genes associated with H3K27me3 in liver (HepG2) and fibroblast (BJ) cell lines. ChIP is available through the Encyclopedia of DNA Elements (ENCODE) (3). I will extract a list of genes with H3K27me3 near the transcription start site (promoter) as well as genes with a broad distribution of H3K27me3 to determine later on if H3K27me3 localization influences Pc-TF function. I will also determine which CBX isoforms are at each locus to determine variations between H3K27me3 sites.	+	*

	==Notes==		==Notes==

Caroline Hom: /* Notes */

Caroline Hom — Mon, 18 Jun 2012 20:59:30 GMT

Notes

←Older revision		Revision as of 20:59, 18 June 2012
Line 17:		Line 17:

	==Notes==		==Notes==
-	* Phase 1 in progress	+	* Phase 2 in progress

Caroline Hom: New page: {|{{table}} width="800" |- |style="background-color: #800000;" align="center"| |align="center" s...

Caroline Hom — Mon, 18 Jun 2012 20:59:14 GMT

New page: {|{{table}} width="800" |- |style="background-color: #800000;" align="center"|  <LNCalendar></LNCalendar>  |align="center" s...

New page

{|{{table}} width="800"
|-
|style="background-color: #800000;" align="center"|

<LNCalendar></LNCalendar>

|align="center" style="background-color: #FFCC00;" |

[[Image:hayneslab2.jpeg|128px]] <sitesearch>title=Search this Project</sitesearch>[[Image:atasu.jpeg|128px]]

|-
|colspan="2" style="background-color: #F2F2F2;" align="right"|[[{{FULLPAGENAME}}/Entry_Base|Customize your entry pages]] [[Help:Notebook/Project_Base/Customize_entry_page|<html><img src="/images/a/aa/Help.png" border="0" /></html>]]
|-
|colspan="2"|
==Project Description/Abstract==
* Since a comprehensive ChIP map is not available for osteosarcoma, I will identify genes associated with H3K27me3 in liver (HepG2) and fibroblast (BJ) cell lines. ChIP is available through the Encyclopedia of DNA Elements (ENCODE) (3). I will extract a list of genes with H3K27me3 near the transcription start site (promoter) as well as genes with a broad distribution of H3K27me3 to determine later on if H3K27me3 localization influences Pc-TF function. I will also determine which CBX isoforms are at each locus to determine variations between H3K27me3 sites.

==Notes==
* Phase 1 in progress

|-
|colspan="2" style="background-color: #F2F2F2;"|
{{LnNotebookRecentChanges2}}
|}

__NOTOC__