Hlavacek

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(Selected Publications)
 
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==Research Interests==
==Research Interests==
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'''Mathematical modeling of complex biological systems'''
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'''Modeling of cellular regulatory systems'''
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*Signal transduction in immmunity and cancer
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*Biomolecular site dynamics
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*Genetic regulatory and metabolic networks
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*Cell signaling in immmunity and cancer  
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*Computational methods and software tools for modeling cellular systems
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*Autophagy
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*Computational methods and software tools  
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'''Bioinformatics'''
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*TF binding site prediction
==Selected Publications==
==Selected Publications==
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*Hlavacek WS, Faeder JR, Blinov ML, Posner RG, Hucka M, Fontana W (2006) Rules for modeling signal-transduction systems. [http://stke.sciencemag.org/ Sci STKE] '''2006''', re6. PMID 16849649
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*Martin KR, Barua D, Kauffman AL, Westrate LM, Posner RG, Hlavacek WS, MacKeigan JP (2013) Computational model for autophagic vesicle dynamics in single cells. [http://www.landesbioscience.com/journals/autophagy/ Autophagy] '''9''', 74-92. PMID 23196898
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*Wall ME, Hlavacek WS, Savageau MA (2004) Design of gene circuits: lessons from bacteria. [http://www.nature.com/nrg/index.html Nat Rev Genet] '''5''', 34-42 PMID 14708014
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*Maienschein-Cline M, Dinner AR, Hlavacek WS, Mu F (2012) Improved predictions of transcription factor binding sites using physicochemical features of DNA. [http://nar.oxfordjournals.org/ Nucleic Acids Res] [http://nar.oxfordjournals.org/content/early/2012/08/24/nar.gks771.full?keytype=ref&ijkey=uzonNxxOdtYY6JN doi: 10.1093/nar/gks771] PMID 22923524
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Research Interests

Modeling of cellular regulatory systems

  • Biomolecular site dynamics
  • Cell signaling in immmunity and cancer
  • Autophagy
  • Computational methods and software tools

Bioinformatics

  • TF binding site prediction

Selected Publications

  • Martin KR, Barua D, Kauffman AL, Westrate LM, Posner RG, Hlavacek WS, MacKeigan JP (2013) Computational model for autophagic vesicle dynamics in single cells. Autophagy 9, 74-92. PMID 23196898


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