Hlavacek: Difference between revisions

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'''Modeling of cellular regulatory systems'''
'''Modeling of cellular regulatory systems'''


*Modeling of cell signaling in immmunity and cancer (biomolecular site dynamics)
*Biomolecular site dynamics
*Bioinformatics (protein-DNA recognition)
*Cell signaling in immmunity and cancer  
*Computational methods and software tools for rule-based modeling
*Autophagy
*Computational methods and software tools  
 
'''Bioinformatics'''
 
*TF binding site prediction


==Selected Publications==
==Selected Publications==


*Hlavacek WS, Faeder JR, Blinov ML, Posner RG, Hucka M, Fontana W (2006) Rules for modeling signal-transduction systems. [http://stke.sciencemag.org/ Sci STKE] '''2006''', re6. PMID 16849649
*Martin KR, Barua D, Kauffman AL, Westrate LM, Posner RG, Hlavacek WS, MacKeigan JP (2013) Computational model for autophagic vesicle dynamics in single cells. [http://www.landesbioscience.com/journals/autophagy/ Autophagy] '''9''', 74-92. PMID 23196898
*Wall ME, Hlavacek WS, Savageau MA (2004) Design of gene circuits: lessons from bacteria. [http://www.nature.com/nrg/index.html Nat Rev Genet] '''5''', 34-42 PMID 14708014
 
*Maienschein-Cline M, Dinner AR, Hlavacek WS, Mu F (2012) Improved predictions of transcription factor binding sites using physicochemical features of DNA. [http://nar.oxfordjournals.org/ Nucleic Acids Res] [http://nar.oxfordjournals.org/content/early/2012/08/24/nar.gks771.full?keytype=ref&ijkey=uzonNxxOdtYY6JN doi: 10.1093/nar/gks771] PMID 22923524


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Latest revision as of 19:34, 6 December 2012

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Research Interests

Modeling of cellular regulatory systems

  • Biomolecular site dynamics
  • Cell signaling in immmunity and cancer
  • Autophagy
  • Computational methods and software tools

Bioinformatics

  • TF binding site prediction

Selected Publications

  • Martin KR, Barua D, Kauffman AL, Westrate LM, Posner RG, Hlavacek WS, MacKeigan JP (2013) Computational model for autophagic vesicle dynamics in single cells. Autophagy 9, 74-92. PMID 23196898
  • Maienschein-Cline M, Dinner AR, Hlavacek WS, Mu F (2012) Improved predictions of transcription factor binding sites using physicochemical features of DNA. Nucleic Acids Res doi: 10.1093/nar/gks771 PMID 22923524