Hoatlin:Projects: Difference between revisions
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'''Chemical Modulation of the FA/BRCA Pathway.''' We designed a rapid, | |||
inexpensive and sensitive cell-free assay to screen for small molecules that modulate the FA/BRCA pathway. We are using this assay to identify potential therapeutic targets and to dissect the activity of the FA proteins within the network of proteins that guard genomic stability.''' | |||
[[Image:frog.png|300px|thumbnail|left|We use proteins from frog eggs to understand the basics about how the Fanconi proteins are involved in DNA replication and repair.]] | [[Image:frog.png|300px|thumbnail|left|We use proteins from frog eggs to understand the basics about how the Fanconi proteins are involved in DNA replication and repair.]] |
Revision as of 12:00, 4 April 2007
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Chemical Modulation of the FA/BRCA Pathway. We designed a rapid, inexpensive and sensitive cell-free assay to screen for small molecules that modulate the FA/BRCA pathway. We are using this assay to identify potential therapeutic targets and to dissect the activity of the FA proteins within the network of proteins that guard genomic stability.
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