Hoatlin:Projects: Difference between revisions
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'''Biochemical analysis of FA protein complexes.''' We are using biochemical assays in Xenopus cell–free extracts together with assays in human cells to identify functionally important proteins and protein complexes in the FA network. | '''Biochemical analysis of FA protein complexes.''' We are using biochemical assays in Xenopus cell–free extracts together with assays in human cells to identify functionally important proteins and protein complexes in the FA network. | ||
'''The role of the FA proteins at early stages of hematopoiesis.''' We identified | '''The role of the FA proteins at early stages of hematopoiesis.''' We identified | ||
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Finger) that binds to FANCC, one of the Fanconi proteins. We are interested in the functional consequences of this interaction in | Finger) that binds to FANCC, one of the Fanconi proteins. We are interested in the functional consequences of this interaction in | ||
normal and dysregulated hematopoiesis. | normal and dysregulated hematopoiesis. | ||
[[Image:frog.png|300px|thumbnail|left|We use proteins from frog eggs to understand the basics about how the Fanconi proteins are involved in DNA replication and repair.]] | [[Image:frog.png|300px|thumbnail|left|We use proteins from frog eggs to understand the basics about how the Fanconi proteins are involved in DNA replication and repair.]] | ||
Revision as of 15:49, 5 October 2006
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