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Our laboratory studies circadian rhythms as a model to better understand how the nervous system regulates
Our laboratory is interested in the function and mechanism of tissue-specific gene expression. This leads us to study many different biological phenomena, including circadian clock outputs, specialization of skeletal muscle, and pathological changes in pulmonary disease. We study the specialization of both mRNA and small ncRNA expression, as well as the functional consequences of their manipulation. We use a combination of functional genomics, bioinformatics, and molecular biology approaches.  
behavior and physiology. We are especially interested in uncovering the mechanisms
driving gene expression rhythms and determining how these molecular oscillations ultimately influence
physiological rhythms. We use a combination of approaches, including ''behavioral neuroscience'', ''molecular biology'', ''genetics'',
''genomics'', and ''bioinformatics''.
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Hughes Lab<br>
Hughes Lab<br>
Pulmonary and Critical Care Medicine<br>
[https://pulmonary.wustl.edu/ Pulmonary and Critical Care Medicine]<br>
Washington University School of Medicine
Washington University School of Medicine
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Latest revision as of 11:09, 10 July 2019

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Our laboratory is interested in the function and mechanism of tissue-specific gene expression. This leads us to study many different biological phenomena, including circadian clock outputs, specialization of skeletal muscle, and pathological changes in pulmonary disease. We study the specialization of both mRNA and small ncRNA expression, as well as the functional consequences of their manipulation. We use a combination of functional genomics, bioinformatics, and molecular biology approaches.




Hughes Lab
Pulmonary and Critical Care Medicine
Washington University School of Medicine