HughesLab:Research

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(System-driven circadian oscillations)
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== Discovery of circadian harmonics ==
== Discovery of circadian harmonics ==
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[[Image:HughesFig1.tif|left|thumb|'''Figure 1''', [http://www.ncbi.nlm.nih.gov/pubmed/19343201 Hughes et al. (2009)]<br>Transcriptional profiling of the mouse liver identified rhythmic transcripts with period lengths of ~8, ~12, and ~24 hours.]]
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[[Image:HughesFig1.tif|left|thumb|'''Figure 1''': [http://www.ncbi.nlm.nih.gov/pubmed/19343201 Hughes et al. (2009)]<br>Transcriptional profiling of the mouse liver identified rhythmic transcripts with period lengths of ~8, ~12, and ~24 hours.]]
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== System-driven circadian oscillations ==
== System-driven circadian oscillations ==
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[[Image:HughesFig2.png|right|thumb|'''Figure 2''']]
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[[Image:HughesFig2.png|right|thumb|'''Figure 2''': [http://www.ncbi.nlm.nih.gov/pubmed/22844252 Hughes et al. (2012b)]<br>~100 genes oscillate in the mouse liver, despite ablation of the local, peripheral clock.]]
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== Rhythms of snoRNA host genes ==
== Rhythms of snoRNA host genes ==
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[[Image:HughesFig3.png|left|thumb|'''Figure 3''': [http://www.ncbi.nlm.nih.gov/pubmed/22472103 Hughes et al. (2012a)]<br>Non-coding, snoRNA host genes oscillate in the fly brain]]
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Revision as of 14:50, 8 January 2013

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Discovery of circadian harmonics

Figure 1: Hughes et al. (2009)Transcriptional profiling of the mouse liver identified rhythmic transcripts with period lengths of ~8, ~12, and ~24 hours.
Figure 1: Hughes et al. (2009)
Transcriptional profiling of the mouse liver identified rhythmic transcripts with period lengths of ~8, ~12, and ~24 hours.














System-driven circadian oscillations

Figure 2: Hughes et al. (2012b)~100 genes oscillate in the mouse liver, despite ablation of the local, peripheral clock.
Figure 2: Hughes et al. (2012b)
~100 genes oscillate in the mouse liver, despite ablation of the local, peripheral clock.









Rhythms of snoRNA host genes

Figure 3: Hughes et al. (2012a)Non-coding, snoRNA host genes oscillate in the fly brain
Figure 3: Hughes et al. (2012a)
Non-coding, snoRNA host genes oscillate in the fly brain









Hughes Lab
Department of Biology
University of Missouri, St. Louis
(Starting in August, 2013)

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