IGEM:Caltech/2007/Project/N: Difference between revisions
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==Role in Lambda Life Cycle== | ==Role in Lambda Life Cycle== | ||
Relative to the two promoters on the chromosome, PL and PR, the N gene lies early in the lambda genome, as depicted in the diagram below. The N protein therefore, acts in the early stages of the phage’s developmental cycle, even before a choice is made between lysis and lysogeny. As shown, it is necessary to turn on the genes to the left of N gene and to the right of cro gene. If the protein is not expressed the mRNA transcripts are terminated in the early stages of development. That is, the phage cannot go into either lytic or lysogenic pathways and it will not be infectious in the absence of N. | |||
==Original Goals== | ==Original Goals== |
Revision as of 08:57, 26 October 2007
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