IGEM:Caltech/2008/Notes

4.14.08: Previous projects

• I'd be willing to also look over USCF if we need to cover all the presentations. - Allem
• I would also be willing to team up with Allen to present UCSF's 2007 Presentation if it's OK with everyone. - Robert
• In regard to the latest email, I'll just do Peking's ppt. -Allen

4.24.08

Papers:

5.1.08

• Josh: Sample Presentation #1
• Chase: Sample Presentation #2

5.8.08

• An incomplete list of project ideas is below. Pick one, or add your own.
  1. Bactofood (food supplement)
  2. Mouthwash (and/or deodorant)
  3. Gut flora engineering
  4. CO2 mineralization
  5. Healthbots (patrolling the blood stream)

Remember, describe the 'big picture' idea, then try to break it down into smaller projects. First look at large pieces - what kinds of abilities would you need (bind to X, produce Y, destroy Z) to accomplish the big picture? Next, think about how you'd produce those abilities (protein α will bind to X, pathway β would produce Y, etc). Bonus points if you can break it down into five separate mini-projects. More bonus points if things would still work with less-than-total success (we need A and B to work to declare success, but C and D would make it cooler. E would be awesome and interesting even if nothing else worked).

5.15.08

• Ideas:
  1. Mouthwash
  2. Bioremediation
  3. Gut flora
  4. Diabetes

• Allen:
• Doug: Artificial White Blood Cells
• Fei: Gut Flora
• Robert: Mouthwash: A Closer Look at Biofilms
• Victoria: Bioremediation

6.5.08

6.12.08

Victoria | Folate Production
Allen | Pop var

6.18.08

Lab jobs

1. LB agar + antibiotic plates : Robert
2. LB media + sterile water : Victoria
3. Wash and autoclave glassware : Fei + Allen
4. Autoclave tips + waste + glass beads, water bath : Doug

Background reading

• Background notes
• Background slides
• Design notes
• Further suggested reading:

1. Elowitz MB and Leibler S. . pmid:10659856. PubMed HubMed [repressilator]
2. Gardner TS, Cantor CR, and Collins JJ. . pmid:10659857. PubMed HubMed [toggle]
3. Adventures in Synthetic Biology [aisb]
4. Fung E, Wong WW, Suen JK, Bulter T, Lee SG, and Liao JC. . pmid:15875027. PubMed HubMed [metabolator]
5. Ro DK, Paradise EM, Ouellet M, Fisher KJ, Newman KL, Ndungu JM, Ho KA, Eachus RA, Ham TS, Kirby J, Chang MC, Withers ST, Shiba Y, Sarpong R, and Keasling JD. . pmid:16612385. PubMed HubMed [artemisinic]
6. Anderson JC, Clarke EJ, Arkin AP, and Voigt CA. . pmid:16330045. PubMed HubMed [tumor]
7. You L, Cox RS 3rd, Weiss R, and Arnold FH. . pmid:15064770. PubMed HubMed [population]
8. Endy D. . pmid:16306983. PubMed HubMed [endy]
9. Voigt CA. . pmid:16978856. PubMed HubMed [voigt]
10. Andrianantoandro E, Basu S, Karig DK, and Weiss R. . pmid:16738572. PubMed HubMed [weiss]