IGEM:Cambridge/2008/Brainstorming

First Day Brainstorming Ideas

Detection

• TNT (other carbon chemicals?)
• Pathogens – difficult as need mammalian cells for antibodies, could combine existing tests in one bacterium/device
• “So that you can smell cancer...” :-S
• Toxins

Mobility

• Use bacterial redopsin, power flagella
• Specific chemotaxis/response to pH

Logic gates

• Compile adder – done by previous team
• Calculator (solving differential equations?)

Outputs

• pH and indicator
• Colour protein (like GFP)
• Voltage? Need to be able to line up bacteria – directionality given in E.coli by nanobrain (attach to mechanism for its positioning)

Misc

• Improve secretion mechanism from E.coli
• Interface biological and electrical systems
• Identifying carcinogens (like Phillip Oliver’s work) – already well developed
• Digest urea in swimming pools, so no need for chlorine etc
• Bio-clock – need reliable biological oscillator
• Targeted delivery
• Active sun cream – displays colour after threshold UV exposure, colour goes if more applied, could produce and release melanin?
• Hair colouring shampoo – fluorescent proteins, can be marketed as “organic”!
• Chameleon bacteria?

Rebecca Koenigsberg-Miles 22:23, 8 July 2008 (UTC):

The Serious Stuff!

Voltage Output

Chris, Rebecca, Marie, Ellis

• Expand Here

Magnetic

Linda, Arjun, Hugo

• Expand Here

Turing Patterns

Xiao-Hu, Daniel, Kevin, Arjun

• Expand Here

Bouyancy

Kathryn, Dmitry, Ian

• Expand Here

Fast Evolution

Daniel, LInda, Kevin, Xiao-Hu

• Expand Here

CO Detection/Metabolism

Dmitriy, James, Ellis, Ian, Arjun

• Mini-review - "Carbon monoxide-dependent energy metabolism in anaerobic bacteria and archaea ' - DOI: 10.1007/s00203-008-0382-6

 - James Wu 00:21, 10 July 2008 (UTC)

Silicate

Hugo

• Expand Here