IGEM:Harvard/2006/DNA nanostructures

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{{IGEM H06 DNA nano navbar}}
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==Project Overview==
==Project Overview==
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**Cell sorting
**Cell sorting
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==Coding==
 
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===Existing code===
 
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*[[IGEM:Harvard/2006/DNA_nanostructures/Designing_DNA_nanostructures|William's code (Python)]]
 
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==Presentations==
 
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===Most recent (Week 3)===
 
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* [[Media:IGEMHarv06 Week3 presentation VKTM2.ppt|Week 3 Presentation: Design Progress]]
 
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===Week 2: Original proposal===
 
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* [[IGEM:Harvard/2006/DNA_nanostructures/Presentation_proposal|Presentation Proposal]]
 
==Working Team Members==
==Working Team Members==
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*[[User:Vlau|Valerie Lau]] ([[User_talk:Vlau|talk]])
*[[User:Vlau|Valerie Lau]] ([[User_talk:Vlau|talk]])
*[[User:Matthewmeisel|Matthew Meisel]] ([[User_talk:Matthewmeisel|talk]])
*[[User:Matthewmeisel|Matthew Meisel]] ([[User_talk:Matthewmeisel|talk]])
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*...and others are welcome!
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==Primary Advisers==
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*[[User:Wmshih|William Shih]] ([[User_talk:Wmshih|talk]])
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*[[User:ShawnDouglas|Shawn Douglas]] ([[User_talk:ShawnDouglas|talk]])

Revision as of 15:05, 11 July 2006


Project Overview

  • Our goal is to to design and implement molecular containers, which can be dynamically opened and closed by an external stimulus.
  • The containers will be implemented as DNA nanostructures, which afford a significant degree of positional control and chemical versatility.
  • As an initial proof-of-concept, we plan to use our DNA containers to demonstrate controllable activation ("delivery") of anti-thrombin aptamers.
  • We expect that molecular containers could have several interesting scientific and clinical applications, such as
    • Drug and gene delivery
    • Bio-marker scavenging (early detection of biomarkers)
    • Directed evolution (compartmentalized selections)
    • Using multiplexing for combinatorial chemical synthesis
    • Capture and stabilization of multiprotein complexes
    • Protein folding (chaperones)
    • Cell sorting


Working Team Members

Primary Advisers

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