IGEM:Harvard/2006/DNA nanostructures
From OpenWetWare
(Difference between revisions)
m |
m (→Recent Changes) |
||
| Line 34: | Line 34: | ||
==Recent Changes== | ==Recent Changes== | ||
| - | {{Special:Recentchanges/b=IGEM:Harvard/2006/DNA_nanostructures&limit= | + | {{Special:Recentchanges/b=IGEM:Harvard/2006/DNA_nanostructures&limit=20}} |
Revision as of 09:53, 14 July 2006
- Project Overview
- Designs
- Notebook
- Protocols
- Presentations
- Literature
Project Overview
- Our goal is to to design and implement molecular containers, which can be dynamically opened and closed by an external stimulus.
- The containers will be implemented as DNA nanostructures, which afford a significant degree of positional control and chemical versatility.
- As an initial proof-of-concept, we plan to use our DNA containers to demonstrate controllable activation ("delivery") of anti-thrombin aptamers.
- We expect that molecular containers could have several interesting scientific and clinical applications, such as
- Drug and gene delivery
- Bio-marker scavenging (early detection of biomarkers)
- Directed evolution (compartmentalized selections)
- Using multiplexing for combinatorial chemical synthesis
- Capture and stabilization of multiprotein complexes
- Protein folding (chaperones)
- Cell sorting
Working Team Members
- Tiffany Chan (talk, edits)
- Katherine Fifer (talk, edits)
- Valerie Lau (talk, edits)
- Matthew Meisel (talk, edits)
- TA: Shawn Douglas (talk, edits)
