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February 23rd 2010
transcription-based circuits: synthetic toggle switch in e. coli
on tuesday, february 23rd, we met once again (!) and discussed this paper:
construction of a genetic toggle switch in Escherichia coli gardner, et al, nature, 2000 
as one of the first examples of using quantitative insight in the engineering of a bistable, transcription-based circuit, this paper helped lay the foundation for further work on synthetic genetic networks. in addition to discussing specifics about the paper’s content, we also used it as an introduction to some of the basic techniques, experimental approaches, and mathematics that are fundamental in the construction of synthetic circuits.
February 9th 2010
Our first meeting will be at 6:30 pm in BioLabs room 1058 (16 Divinity Ave, Cambridge MA). We will be discussing the Nature Editorial "Meanings of 'Life'". Join us for pizza and exciting discussion about the definition of synthetic biology and how it can affect our definitions of life.