IGEM:IMPERIAL/2007/Projects/Hrp System/Modelling: Difference between revisions

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==Mathematical Modelling==
==Mathematical Modelling==
<br>
===Modelling Gene Regulation===
===Modelling Gene Regulation===
====Mechanisms of Prokaryotic Gene Regulation====
====Mechanisms of Prokaryotic Gene Regulation====

Latest revision as of 23:37, 22 July 2007

Hrp Characterisation: Modelling



                                                       (under construction)


Computational Modelling

Computational modelling offers a means of studying complex biological systems in silico.

Cell Designer

A process-diagram editor for modelling complex gene-regulation and biochemical pathways.

VCell


Mathematical Modelling

Modelling Gene Regulation

Mechanisms of Prokaryotic Gene Regulation

Transcription
  • Transcriptional Activation
  • Transcriptional Repression
Translation



Regulatory Motifs

Negative feedback

  • Mechanism of operation
  • Steady state
  • Stability
  • Sensitivity
  • Response time
  • Noise reduction