IGEM:IMPERIAL/2007/Projects/Modelling/Notes: Difference between revisions

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Consider the following transcription interaction:
Consider the following transcription interaction:
<math>X \rightarrow Y</math> , where <math>X</math> is a transcription factor; <math>Y</math> is a protein product of gene ''y'' whose activity is regulated.
<math>X \rightarrow Y</math> , where <math>X</math> is a transcription factor; <math>Y</math> is a protein product of gene ''y'' whose activity is regulated. The task involves determining the dynamics of the reaction, involving the concentration of protein <math>Y</math> and its response time.
Protein production is balanced by the opposing processes: protein ''degradation'' and ''dilution''. Degradation refers to the breakdown of proteins; dilution, a reduction in the concentration of the protein due to an increase of cellular volume, a consequence of cellular growth.

Revision as of 07:35, 27 July 2007

Modelling: Notes


This section shall be expanded systematically. Furthermore, the tutorial on Modelling Techniques will hopefully be held on Monday, 30 July 2007.


Dynamics and Response Time of Gene Regulation

Consider the following transcription interaction: [math]\displaystyle{ X \rightarrow Y }[/math] , where [math]\displaystyle{ X }[/math] is a transcription factor; [math]\displaystyle{ Y }[/math] is a protein product of gene y whose activity is regulated. The task involves determining the dynamics of the reaction, involving the concentration of protein [math]\displaystyle{ Y }[/math] and its response time. Protein production is balanced by the opposing processes: protein degradation and dilution. Degradation refers to the breakdown of proteins; dilution, a reduction in the concentration of the protein due to an increase of cellular volume, a consequence of cellular growth.