IGEM:IMPERIAL/2008/New/Growth Curve
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* Stationary phase:  * Stationary phase:  
** Occurs from 10s – 15 s. Bacterial growth curve has ceased, hence the gradient of the growth curve does not change at this stage.  ** Occurs from 10s – 15 s. Bacterial growth curve has ceased, hence the gradient of the growth curve does not change at this stage.  
  
  
** Explanation:  ** Explanation:  
  
*** The assumption that the concentration of external nutrients is finite is included in this model  *** The assumption that the concentration of external nutrients is finite is included in this model  
  
  
*** Also, the behaviour of a bacteria consuming nutrients during its growth is incorporated in the model, hence the stationary phase  *** Also, the behaviour of a bacteria consuming nutrients during its growth is incorporated in the model, hence the stationary phase  
  
* For data analysis  * For data analysis  
** To characterise the chassis, we want to determine  ** To characterise the chassis, we want to determine  
  +  *** Time span of lag phase, stationary phase and exponential phase  
  ***  +  *** The growth rate 
  +  *** The error of each experiments  
  ***  +  
  +  
  ***  +  
==Discussion==  ==Discussion== 
Revision as of 13:16, 11 September 2008
 
Growth CurvesAuthors: Erika and Prudence Editors: Erika Upload Mattieu's tutorials Why model the growth curve?To characterise the B. subtilis chassis that we are using. How to model the growth curve?In order to model the growth of B. subtilis, the process was broken down into three main steps where a submodel is produced in MATLAB in each step. Each submodel is an ODE model which can be simulated using MATLAB. The variables in each submodel are modified. So in the final step, a combination of submodel 1 and 2 are incorporated with submodel 3, resulting in a more complex model which illustrates the behaviour of bacterial growth. For more details about the process of building the model click on the following link: Tutorial for Growth curve.
The Model
DiscussionGrowth Curve
