IGEM:MIT/2008/Notebook/Yogurt

(Difference between revisions)

Revision as of 16:21, 16 June 2008

Our goal is to engineer a common yogurt bacteria, Lactobacillus bulgaricus, so that it will express the 20aa peptide p1025. A |clinical study reports that p1025 is good for your teeth (p1025 reduces oral colonization of a Streptococcus mutans, a tooth-decaying bacterium).

We will express P1050 in E. coli as an intermediate step to evaluate protein secretion and efficacy.

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 ==Description==
-We seek to express the 20aa peptide P1050 in Lactobacillus bulgaricus/lactis.
+*Our goal is to engineer a common yogurt bacteria, Lactobacillus bulgaricus, so that it will express the 20aa peptide p1025. A [http://www.ncbi.nlm.nih.gov/pubmed/9920267?dopt=Abstract |clinical study] reports that p1025 is good for your teeth (p1025 reduces oral colonization of a Streptococcus mutans, a tooth-decaying bacterium).
-We will express P1050 in E. coli as an intermediate step to evaluate protein secretion and efficacy.
+*We will express P1050 in E. coli as an intermediate step to evaluate protein secretion and efficacy.
 ==Notes==