IGEM:Paris Bettencourt 2012/Notebooks/Delay group: Difference between revisions

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<center>'''Delay group'''</center>


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== <center>'''Delay group'''</center> ==
 


The aim of that subproject is to find a way to launch the destruction of either the construction or the organism after a certain laps of time.
The aim of that subproject is to find a way to launch the destruction of either the construction or the organism after a certain laps of time.
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Here we report the idea we have, and how we could make them real.
Here we report the idea we have, and how we could make them real.


*Alginate beads.
===Alginate beads===
Here we would place alginate beads, with controlled alginate matrix size into the capsule. The alginate beads contains Theophylline, that would act as an activator of a riboswitch
Here, we would place alginate beads, with controlled alginate matrix size into the capsule. The alginate beads contains theophylline, that would act as an activator of a [http://en.wikipedia.org/wiki/Riboswitch| riboswitch] that would repress gene expression <ref>Topp et. al, 2008</ref>.
 
== Notes ==
{{reflist}}
 
== References ==
1. Topp, S. & Gallivan, J.P. Riboswitches in unexpected places -€” A synthetic riboswitch in a protein coding region. RNA journal 2498-2503 (2008) [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2590966/| Paper]

Revision as of 05:10, 25 June 2012

Notebook Design Roadmap Meetings and to-dos Protocols Bibliography Previous Biosafety iGEM projects



Delay group

The aim of that subproject is to find a way to launch the destruction of either the construction or the organism after a certain laps of time.

Here we report the idea we have, and how we could make them real.

Alginate beads

Here, we would place alginate beads, with controlled alginate matrix size into the capsule. The alginate beads contains theophylline, that would act as an activator of a riboswitch that would repress gene expression [1].

Notes

  1. Topp et. al, 2008

References

1. Topp, S. & Gallivan, J.P. Riboswitches in unexpected places -€” A synthetic riboswitch in a protein coding region. RNA journal 2498-2503 (2008) Paper