IGEM:PennState/Labbook/Nimrah Ahmed

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Meeting 5/15/2008

Circuit project ideas:

  • Genetic Circuit basics: http://www.princeton.edu/~rweiss/bio-programming/weiss-natural-computing-2003.pdf
  • Sequential cell color change
    • ex. Green->Red->Yellow->repeat.
    • System: organic layer & bacterial aquatic layer in liquid form. Shake to combine organic layer w/ bacterial aquatic layer -> initiate color change.
    • Structure: Messenger protein downstream of color protein, downstream of organic molecule-activated promoter
    • Rather than shake, stir by thermal convection or a magnetic stirrer
    • Bioluminescense : proteins like "M-Cherry" instead of flourescent proteins...

(Peking U did something like this--sequential color change--but UV activated. MIT team idea: bacterial lava lamp?)

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