IGEM:PennState/Labbook/Nimrah Ahmed

Meeting 5/15/2008

Circuit project ideas:

• Genetic Circuit basics: http://www.princeton.edu/~rweiss/bio-programming/weiss-natural-computing-2003.pdf
• Sequential cell color change
  • ex. Green->Red->Yellow->repeat.
  • System: organic layer & bacterial aquatic layer in liquid form. Shake to combine organic layer w/ bacterial aquatic layer -> initiate color change.
  • Structure: Messenger protein downstream of color protein, downstream of organic molecule-activated promoter
  • Rather than shake, stir by thermal convection or a magnetic stirrer
  • Bioluminescense : proteins like "M-Cherry" instead of flourescent proteins...

(Peking U did something like this--sequential color change--but UV activated. MIT team idea: bacterial lava lamp?)