IGEM:Stanford/2009/GCPR: Difference between revisions

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Properties and Kinetics," article from Biophysical Journal, March 2009: http://www.cell.com/biophysj/fulltext/S0006-3495(09)00016-2
Properties and Kinetics," article from Biophysical Journal, March 2009: http://www.cell.com/biophysj/fulltext/S0006-3495(09)00016-2
*Engineering G protein-coupled receptor expression in bacteria, article from PNAS, Sept. 2008: http://www.pnas.org/content/105/39/14747.full
*Engineering G protein-coupled receptor expression in bacteria, article from PNAS, Sept. 2008: http://www.pnas.org/content/105/39/14747.full
*Database of Membrane Protein Structures: http://blanco.biomol.uci.edu/Membrane_Proteins_xtal.html


==Questions==
==Questions==
*I would highly recommend looking through George Georgiou's literature to see what engineered parts he has made. - Chris
*I would highly recommend looking through George Georgiou's literature to see what engineered parts he has made. - Chris

Revision as of 16:50, 3 May 2009

Summary

Comments and Discussion

  • Can we identify a specific GPCR or class of GPCRs that we are interested in manipulating?
  • Which host organism would make the best chassis?
  • What should our GPCR be sensitive to?

Papers

  • "Characterization of Engineered Channelrhodopsin Variants with Improved

Properties and Kinetics," article from Biophysical Journal, March 2009: http://www.cell.com/biophysj/fulltext/S0006-3495(09)00016-2

Questions

  • I would highly recommend looking through George Georgiou's literature to see what engineered parts he has made. - Chris