IGEM:UIUC/Software/2010/2010/03/10: Difference between revisions
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==Entry | <!-- | ||
* | ==March 10, 2010== | ||
===First Entry=== | |||
* Information about Dijkstras -- searches network to get from one network to another | |||
<br/> | |||
* Many metabolic pathways | |||
** FBA - flux balance analysis | |||
** COBRA - (matlab) -- links things | |||
** KEGG - pathway maths | |||
** Environmental strains? - secondary enzymes | |||
** Crossing over pathways -- KEGG map -- galactose metabolism pathway -- enzymes, collecting compounds - group the enzymes to compounds | |||
*** Things can cross over and can be done in a different way | |||
*** They highlighted (competing people) -- intermediate pathways | |||
** Metabolic | |||
* Continue code - pathway - nodes = products , lines = reactions (IMP) | |||
** Fewest constraints -- tried | |||
** Problems -- compounds are isolated -- some only connected in one way | |||
** Shortest path algorithm -- defined edge of dot product numbers we know and numbers we give it -- weights you define and facts (number of things) = a number == length of the edge (bad facts) -- | |||
** Number of connectivity -- about 100 -- how many different compounds is each connected too -- each on its own scale -- dot matrices don't line up .. [0 1] . [~1 100] | |||
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** How pathway effects cell (host) | |||
*** Host = hypothetical host | |||
* '''TO BE IMPRESSIVE AT IGEM''' | |||
** Gotta be impressive! -- tweak a lot | |||
** Add massive new feature -- say how pathway would effect overall system | |||
** Many metabolic -- gotta really do something with it | |||
* Biobrick - | |||
** Freiburg | |||
* Look at previous iGEM -- iGEM website -- Francis does this | |||
** Do use biobricks in some way | |||
* Google group -- check | |||
* Completely Different: | |||
** Working with the wetlab - | |||
*** model their current project? | |||
**** Cellular logic design - takes substance and fluoresces colors depending on two different things - working toward cellular computation -- (0s and 1s) -- more analog -- end goal: computation of things within a cell -- direct diseases | |||
***** Don't fluoresce, next step: release -- outputs and inputs produce things -- and, or gates | |||
***** Designer tool -- EC majors -- lay out-- coverts to biobricks | |||
***** See IBE person | |||
** Analyzing wetlab team -- give them a helping hand -- make smoother process | |||
*** Different interference sequence in wire diagram -- and: promoter promotes certain region which upreglates something else which gives you a specfic fluorescence | |||
**** Do a small model -- help our team by simulating | |||
**** OR as just a side project | |||
<br/> | |||
* Must come up with a way to keep track of all journals read -- for citing. | |||
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<br/> | |||
'''Homework''' - look at all the old projects (software projects) -- and look up biobricks - go onto iGEM websites and check the schedule post -- color coated by category. Go through judging requirements | |||
** Modeling, safety, biobricks -- force your really cool idea into iGEM judging | |||
** Split up stuff to collect research -- Anna -- metabolic pathways, | |||
** Look up research from previous years | |||
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[[category:OWWLabNotebookV1]] | [[category:OWWLabNotebookV1]] |
Revision as of 16:35, 29 May 2010
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