IGEM:VGEM/2007/Projects: Difference between revisions
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====References==== | ====References==== | ||
*[http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=1367455 Melanin production in Escherichia coli from a cloned tyrosinase gene by Della-Cioppa G, Garger SJ, Sverlow GG, Turpen TH, Grill LK.] | *[http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=1367455 ''Melanin production in Escherichia coli from a cloned tyrosinase gene'' by Della-Cioppa G, Garger SJ, Sverlow GG, Turpen TH, Grill LK.] | ||
===Ethylene Biosensor=== | ===Ethylene Biosensor=== | ||
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*[http://www.ncbi.nlm.nih.gov/sites/entrez ''The ethylene gas signal transduction pathway: a molecular perspective'' by Johnson PR, Ecker JR.] | |||
===Synthetic Biological Clock=== | ===Synthetic Biological Clock=== | ||
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The synthetic biological clock was one of our earliest project ideas and involves the coupling of Elowitz and Leibler's repressilator system to some actuator such as fluorescence or aroma generation. We would like to link MIT's 2006 iGEM project to the repressilator and create an aroma therapy clock in addition to linking green, yellow and red fluorescent proteins to the repressilator to make a molecular traffic light. Future applications of controlled synthetic oscillatory systems include internal, autonomous drug delivery technology. | The synthetic biological clock was one of our earliest project ideas and involves the coupling of Elowitz and Leibler's repressilator system to some actuator such as fluorescence or aroma generation. We would like to link MIT's 2006 iGEM project to the repressilator and create an aroma therapy clock in addition to linking green, yellow and red fluorescent proteins to the repressilator to make a molecular traffic light. Future applications of controlled synthetic oscillatory systems include internal, autonomous drug delivery technology. | ||
====References==== | ====References==== | ||
Revision as of 09:32, 4 June 2007
Projects
Bacterial Melanogenesis
This project is an extension of work that was done at Biosource Genetics Corporation in 1990. What we would like to do is program bacteria to produce melanin in response to a red light stimulus. This inducible melanin production has various applications including making melanin for monitoring cellular processes. In this way, melanin would serve as a biomarker or indicator similar to the GFP but would be easily visible to the naked eye.
References
Ethylene Biosensor
During one of our brainstorming sessions we were discussing possible biosensors and came up with a fairly practical project idea: an ethylene biosensor. Why sense ethylene? Mature fruit produce and release ethylene as they ripen. Measuring the concentration of gaseous ethylene on or near the surface of the ripening fruit would allow for the indirect measurement of its degree of ripeness.
References
Synthetic Biological Clock
The synthetic biological clock was one of our earliest project ideas and involves the coupling of Elowitz and Leibler's repressilator system to some actuator such as fluorescence or aroma generation. We would like to link MIT's 2006 iGEM project to the repressilator and create an aroma therapy clock in addition to linking green, yellow and red fluorescent proteins to the repressilator to make a molecular traffic light. Future applications of controlled synthetic oscillatory systems include internal, autonomous drug delivery technology.
