This project is an extension of work that was done at Biosource Genetics Corporation in 1990. What we would like to do is program bacteria to produce melanin in response to a red light stimulus. This inducible melanin production has various applications including making melanin for monitoring cellular processes. In this way, melanin would serve as a biomarker or indicator similar to the GFP but would be easily visible to the naked eye.
- Melanin production in Escherichia coli from a cloned tyrosinase gene by Della-Cioppa G, Garger SJ, Sverlow GG, Turpen TH, Grill LK.