Imperial College/Courses/Spring2008/Synthetic Biology/SB Lecture 3: Difference between revisions
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* [[Media:Vincent_Rouilly_SynBio_Course_Topic_3.pdf | Slides (PDF format, 2M)]] | * [[Media:Vincent_Rouilly_SynBio_Course_Topic_3.pdf | Slides (PDF format, 2M)]] | ||
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<font face="trebuchet ms" style="color:#FFFFFF" size="3">''' Resources / References :'''</font><br> | <font face="trebuchet ms" style="color:#FFFFFF" size="3">''' Resources / References :'''</font><br> | ||
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* | * [[BE.180:Devices | Devices explained (from Endy, BE.180 MIT)]] | ||
* [http://www.nature.com/nature/comics/syntheticbiologycomic/index.html "Adventures in Synthetic Biology" Comic] | |||
* [[PoPS | Definition of Polymerases per second (PoPS)]] | |||
* [[RiPS | Definition of Ribosomes per second (RiPS)]] | |||
* [[Endy:Standard_for_composable_inverters/Repressor_kinetics | Standard for composable inverters (Endy's Lab)]] | |||
* [[Registry_of_standard_biological_parts/Composable_Inverter_Family | Composable Inverter Family (Jason Kelly, MIT)]] | |||
* Modular PoPS devices from iGEM projects: | |||
** [http://parts.mit.edu/igem07/index.php/Cambridge/Amplifier_project iGEM Amplifier (Cambridge 2007)] | |||
** [http://parts.mit.edu/igem07/index.php/Valencia/Promoter_calibrator iGEM comparator (Valencia 2007)] | |||
** [http://parts.mit.edu/igem07/index.php/Peking_The_Projects iGEM Peking 2007] | |||
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Synthetic Biology Lectures (under development...)
PoPs and RiPs: transcriptional device standards for functional composition
Instructor: Vincent Rouilly
Date: 20th February 2008
Room: Room 1, Whiteleys Suite, RCS1 building.
Objectives:
- Quick refresh on gene expression using BioBrick parts: transcription / translation / DNA-binding protein
- Abstraction layers: DNA --> Promoter / RBS / ORF / Terminator --> Protein Generator / Genetic Inverter
- Standard biological information flow : Polymerase per second (PoPS), Ribosomes per second (RiPS)
- Modular inverter design (RiPS based or PoPs based)
- Modular and re-usable designs
Presentation Slides:
Resources / References :
- Devices explained (from Endy, BE.180 MIT)
- "Adventures in Synthetic Biology" Comic
- Definition of Polymerases per second (PoPS)
- Definition of Ribosomes per second (RiPS)
- Standard for composable inverters (Endy's Lab)
- Composable Inverter Family (Jason Kelly, MIT)
- Modular PoPS devices from iGEM projects:
