In Vivo Mechanical Stimulation of Tissues by Tyler Russell

Mechanical stimulation can be used to accelerate the proliferation of certain types of cells and is consequently quite useful in several tissue engineering applications. Mechanical stimulation of tissue can occur both in vivo and in vitro, although most in vitro environments used for such stimulation would likely mimic an in vivo environment. Cell types of interest for mechanical stimulation of tissue in vivo primarily include osteoblasts as well as tendon derived stem cells (TDSCs). Multiple studies have shown that in vivo stimulation of these types of tissue can increase differentiation and development rate.

In contrast to the increased proliferation of some cells with the proper mechanical stimulation, tumor cells and tissues may undergo cytotoxic effects when exposed to