Jacobs - Revision history

An M. Nguyen: /* News */

An M. Nguyen — Thu, 08 Mar 2012 20:55:51 GMT

News

←Older revision		Revision as of 20:55, 8 March 2012
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	==News==		==News==
-	*'''02/04/2012 CMBL Postdoctoral Fellow David Hoey and Graduate Students Kristen Lee and An Nguyen presented at the Orthopaedic Research Society 2012 Annual Meeting in San Francisco'''	+	*'''2/14/2012 CMBL's NIH R01 grant for ~$2 million over 5 years gets approved'''
		+	The grant was entitled "Primary cilia as mechanotransducers in bone". The long-term goal of this project is to determine how primary cilia contribute to bone’s ability to sense and respond to mechanical loading.
		+
		+	*'''2/4/2012 CMBL Postdoctoral Fellow David Hoey and Graduate Students Kristen Lee and An Nguyen presented at the Orthopaedic Research Society 2012 Annual Meeting in San Francisco'''
	Dr. Hoey's talk was entitled "A mechanosensory role for the primary cilium in human mesenchymal stem cells". Congratulations Dr. Hoey for being selected as New Investigator Recognition Award finalist.		Dr. Hoey's talk was entitled "A mechanosensory role for the primary cilium in human mesenchymal stem cells". Congratulations Dr. Hoey for being selected as New Investigator Recognition Award finalist.
	Kristen's poster was entitled "Adenylyl cyclase 6 mediates bone adapatation in vivo".		Kristen's poster was entitled "Adenylyl cyclase 6 mediates bone adapatation in vivo".

An M. Nguyen at 20:44, 1 March 2012

An M. Nguyen — Thu, 01 Mar 2012 20:44:27 GMT

←Older revision		Revision as of 20:44, 1 March 2012
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	Abstracts for these papers are available on the SPRBM website (http://www.sprbm.org/assets/bmessprbm2011programbook.pdf)'''		Abstracts for these papers are available on the SPRBM website (http://www.sprbm.org/assets/bmessprbm2011programbook.pdf)'''

-	*'''1/16/2010 CMBL Postdoctoral Fellow David Hoey awarded Best Presentation at the 28th meeting of the SPRBM'''	+	*'''1/16/2010 CMBL Postdoctoral Fellow David Hoey awarded Best Presentation at the 28th meeting of the SPRBM in Miami'''
	Postdoctoral fellow David Hoey was awarded best presentation in the Postdoctoral Category at the 28th meeting of the Society of Physical Regulation in Biology and Medicine. His paper was entitled “Determining the mechanisms of primary cilia bending in response to fluid shear stress”. This paper along with fellow CMBL member, graduate student Jennifer Blundo’s paper are available on the SPRBM website (http://www.pitt.edu/~sprbm/index.html)		Postdoctoral fellow David Hoey was awarded best presentation in the Postdoctoral Category at the 28th meeting of the Society of Physical Regulation in Biology and Medicine. His paper was entitled “Determining the mechanisms of primary cilia bending in response to fluid shear stress”. This paper along with fellow CMBL member, graduate student Jennifer Blundo’s paper are available on the SPRBM website (http://www.pitt.edu/~sprbm/index.html)

An M. Nguyen: /* News */

An M. Nguyen — Thu, 01 Mar 2012 20:24:22 GMT

News

←Older revision		Revision as of 20:24, 1 March 2012
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	*'''12/12/2011 CMBL Postdoctoral Fellow David Hoey and Graduate Student Kristen Lee presented talks at the 4th International Conference on Mechanics of Biomaterials and Tissues'''		*'''12/12/2011 CMBL Postdoctoral Fellow David Hoey and Graduate Student Kristen Lee presented talks at the 4th International Conference on Mechanics of Biomaterials and Tissues'''
-	Dr. Hoey's talk was entitled "The mechanosensing role of the primary cilium in oscillatory fluid flow driven osteogenic differentiation of human bone marrow stromal cells"	+	Dr. Hoey's talk was entitled "The mechanosensing role of the primary cilium in oscillatory fluid flow driven osteogenic differentiation of human bone marrow stromal cells".
-	Kristen's talk was entitled "Adenylyl cyclase 6 mediates in vivo mechanotransduction in bone"	+	Kristen's talk was entitled "Adenylyl cyclase 6 mediates in vivo mechanotransduction in bone".

	*'''4/30/2011 CMBL Postdoctoral Fellow David Hoey awarded certificate for Outstanding Trainee Presentation at the 4th New York Skeletal Biology and Medicine Conference'''		*'''4/30/2011 CMBL Postdoctoral Fellow David Hoey awarded certificate for Outstanding Trainee Presentation at the 4th New York Skeletal Biology and Medicine Conference'''
-	His paper was entitled "A role for the primary cilium in fluid flow mediatd osteogenic differentiation of human mesenchymal stem cells"	+	His paper was entitled "A role for the primary cilium in fluid flow mediatd osteogenic differentiation of human mesenchymal stem cells".

	*'''4/4/2011 CMBL Graduate Student Kristen Lee was awarded a 2011 National Science Foundation (NSF) Graduate Research Fellowship Program (GRFP) Fellowship'''		*'''4/4/2011 CMBL Graduate Student Kristen Lee was awarded a 2011 National Science Foundation (NSF) Graduate Research Fellowship Program (GRFP) Fellowship'''

An M. Nguyen at 20:23, 1 March 2012

An M. Nguyen — Thu, 01 Mar 2012 20:23:23 GMT

←Older revision		Revision as of 20:23, 1 March 2012
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	==News==		==News==
		+	*'''02/04/2012 CMBL Postdoctoral Fellow David Hoey and Graduate Students Kristen Lee and An Nguyen presented at the Orthopaedic Research Society 2012 Annual Meeting in San Francisco'''
		+	Dr. Hoey's talk was entitled "A mechanosensory role for the primary cilium in human mesenchymal stem cells". Congratulations Dr. Hoey for being selected as New Investigator Recognition Award finalist.
		+	Kristen's poster was entitled "Adenylyl cyclase 6 mediates bone adapatation in vivo".
		+	An's poster was entitled "Oscillatory fluid flow increases expression of inversin in mesenchymal stem cells".
		+
	*'''12/12/2011 CMBL Postdoctoral Fellow David Hoey and Graduate Student Kristen Lee presented talks at the 4th International Conference on Mechanics of Biomaterials and Tissues'''		*'''12/12/2011 CMBL Postdoctoral Fellow David Hoey and Graduate Student Kristen Lee presented talks at the 4th International Conference on Mechanics of Biomaterials and Tissues'''
	Dr. Hoey's talk was entitled "The mechanosensing role of the primary cilium in oscillatory fluid flow driven osteogenic differentiation of human bone marrow stromal cells"		Dr. Hoey's talk was entitled "The mechanosensing role of the primary cilium in oscillatory fluid flow driven osteogenic differentiation of human bone marrow stromal cells"

Kristen L. Lee at 20:06, 1 March 2012

Kristen L. Lee — Thu, 01 Mar 2012 20:06:47 GMT

←Older revision		Revision as of 20:06, 1 March 2012
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	Welcome to the Cell and Molecular Biomechanics Lab! CMBL is part of the [http://bme.columbia.edu Department of Biomedical Engineering] at [http://www.columbia.edu Columbia University]! The CMBL is focused on determining the mechanism that allows cells to sense and respond to extracellular mechanical stimulation. Particularly we are interested in determining, at a cellular level, how bone tissue is regulated by physical loading. This work has applications in developing new therapies to age-related bone loss and osteoporosis. We explore this question both in cell culture identifying novel molecular targets and in quantifying the skeletal sensitivity to loading of tissue-specific conditional deletions in mice. Our current targets include focal adhesions, cytoskeletal proteins, and the cell's primary cilium.		Welcome to the Cell and Molecular Biomechanics Lab! CMBL is part of the [http://bme.columbia.edu Department of Biomedical Engineering] at [http://www.columbia.edu Columbia University]! The CMBL is focused on determining the mechanism that allows cells to sense and respond to extracellular mechanical stimulation. Particularly we are interested in determining, at a cellular level, how bone tissue is regulated by physical loading. This work has applications in developing new therapies to age-related bone loss and osteoporosis. We explore this question both in cell culture identifying novel molecular targets and in quantifying the skeletal sensitivity to loading of tissue-specific conditional deletions in mice. Our current targets include focal adhesions, cytoskeletal proteins, and the cell's primary cilium.
	</font>		</font>
-	<center>[[Image:~~GroupPhoto2010~~.~~jpg~~ \| ~~300px~~]]</center>	+	<center>[[Image:lab pictures website.png \| 500px]]</center>


-	==News==~~[[Image:lab pictures website.png]]~~	+	==News==
	*'''12/12/2011 CMBL Postdoctoral Fellow David Hoey and Graduate Student Kristen Lee presented talks at the 4th International Conference on Mechanics of Biomaterials and Tissues'''		*'''12/12/2011 CMBL Postdoctoral Fellow David Hoey and Graduate Student Kristen Lee presented talks at the 4th International Conference on Mechanics of Biomaterials and Tissues'''
	Dr. Hoey's talk was entitled "The mechanosensing role of the primary cilium in oscillatory fluid flow driven osteogenic differentiation of human bone marrow stromal cells"		Dr. Hoey's talk was entitled "The mechanosensing role of the primary cilium in oscillatory fluid flow driven osteogenic differentiation of human bone marrow stromal cells"

Kristen L. Lee: /* News */

Kristen L. Lee — Thu, 01 Mar 2012 20:03:37 GMT

News

←Older revision		Revision as of 20:03, 1 March 2012
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-	==News==	+	==News==[[Image:lab pictures website.png]]
	*'''12/12/2011 CMBL Postdoctoral Fellow David Hoey and Graduate Student Kristen Lee presented talks at the 4th International Conference on Mechanics of Biomaterials and Tissues'''		*'''12/12/2011 CMBL Postdoctoral Fellow David Hoey and Graduate Student Kristen Lee presented talks at the 4th International Conference on Mechanics of Biomaterials and Tissues'''
	Dr. Hoey's talk was entitled "The mechanosensing role of the primary cilium in oscillatory fluid flow driven osteogenic differentiation of human bone marrow stromal cells"		Dr. Hoey's talk was entitled "The mechanosensing role of the primary cilium in oscillatory fluid flow driven osteogenic differentiation of human bone marrow stromal cells"

Kristen L. Lee: /* News */

Kristen L. Lee — Thu, 15 Dec 2011 06:06:19 GMT

News

←Older revision		Revision as of 06:06, 15 December 2011
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	His paper was entitled "A role for the primary cilium in fluid flow mediatd osteogenic differentiation of human mesenchymal stem cells"		His paper was entitled "A role for the primary cilium in fluid flow mediatd osteogenic differentiation of human mesenchymal stem cells"

-	*'''4/4/2011 CMBL Graduate Student Kristen Lee was awarded ~~the~~ National Science Foundation Graduate Research Fellowship.'''	+	*'''4/4/2011 CMBL Graduate Student Kristen Lee was awarded a 2011 National Science Foundation (NSF) Graduate Research Fellowship Program (GRFP) Fellowship'''
		+	Selection was based on her outstanding abilities and accomplishments and potential to contribute to strengthening the vitality of the US science and engineering enterprise. Funding for three years of doctoral studies are included in the award.

	*'''1/8/2011 CMBL Graduate Students Kristen Lee and Matthew Downs awarded travel grants and Postdoctoral Fellow Julia Chen awarded Best Podium at the 29th meeting of the SPRBM'''		*'''1/8/2011 CMBL Graduate Students Kristen Lee and Matthew Downs awarded travel grants and Postdoctoral Fellow Julia Chen awarded Best Podium at the 29th meeting of the SPRBM'''

Kristen L. Lee: /* News */

Kristen L. Lee — Thu, 15 Dec 2011 06:02:10 GMT

News

←Older revision		Revision as of 06:02, 15 December 2011
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	==News==		==News==
		+	*'''12/12/2011 CMBL Postdoctoral Fellow David Hoey and Graduate Student Kristen Lee presented talks at the 4th International Conference on Mechanics of Biomaterials and Tissues'''
		+	Dr. Hoey's talk was entitled "The mechanosensing role of the primary cilium in oscillatory fluid flow driven osteogenic differentiation of human bone marrow stromal cells"
		+	Kristen's talk was entitled "Adenylyl cyclase 6 mediates in vivo mechanotransduction in bone"
		+
	*'''4/30/2011 CMBL Postdoctoral Fellow David Hoey awarded certificate for Outstanding Trainee Presentation at the 4th New York Skeletal Biology and Medicine Conference'''		*'''4/30/2011 CMBL Postdoctoral Fellow David Hoey awarded certificate for Outstanding Trainee Presentation at the 4th New York Skeletal Biology and Medicine Conference'''
	His paper was entitled "A role for the primary cilium in fluid flow mediatd osteogenic differentiation of human mesenchymal stem cells"		His paper was entitled "A role for the primary cilium in fluid flow mediatd osteogenic differentiation of human mesenchymal stem cells"
		+
		+	*'''4/4/2011 CMBL Graduate Student Kristen Lee was awarded the National Science Foundation Graduate Research Fellowship.'''

	*'''1/8/2011 CMBL Graduate Students Kristen Lee and Matthew Downs awarded travel grants and Postdoctoral Fellow Julia Chen awarded Best Podium at the 29th meeting of the SPRBM'''		*'''1/8/2011 CMBL Graduate Students Kristen Lee and Matthew Downs awarded travel grants and Postdoctoral Fellow Julia Chen awarded Best Podium at the 29th meeting of the SPRBM'''

David Hoey: /* News */

David Hoey — Wed, 04 May 2011 13:55:40 GMT

News

←Older revision		Revision as of 13:55, 4 May 2011
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	==News==		==News==
		+	*'''4/30/2011 CMBL Postdoctoral Fellow David Hoey awarded certificate for Outstanding Trainee Presentation at the 4th New York Skeletal Biology and Medicine Conference'''
		+	His paper was entitled "A role for the primary cilium in fluid flow mediatd osteogenic differentiation of human mesenchymal stem cells"
		+
	*'''1/8/2011 CMBL Graduate Students Kristen Lee and Matthew Downs awarded travel grants and Postdoctoral Fellow Julia Chen awarded Best Podium at the 29th meeting of the SPRBM'''		*'''1/8/2011 CMBL Graduate Students Kristen Lee and Matthew Downs awarded travel grants and Postdoctoral Fellow Julia Chen awarded Best Podium at the 29th meeting of the SPRBM'''
	Kristen Lee presented a paper entitled "TRPV4 is required for mechanotransduction in MC3T3 osteoblasts".'''		Kristen Lee presented a paper entitled "TRPV4 is required for mechanotransduction in MC3T3 osteoblasts".'''

An M. Nguyen at 23:44, 4 March 2011

An M. Nguyen — Fri, 04 Mar 2011 23:44:18 GMT

←Older revision		Revision as of 23:44, 4 March 2011
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