Jacobs:Research - Revision history

An M. Nguyen at 22:55, 2 December 2011

An M. Nguyen — Fri, 02 Dec 2011 22:55:06 GMT

←Older revision		Revision as of 22:55, 2 December 2011
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	[[Jacobs:Research:Loading Induced Fluid Flow and Disuse Bone Loss\|Loading Induced Fluid Flow and Disuse Bone Loss]]		[[Jacobs:Research:Loading Induced Fluid Flow and Disuse Bone Loss\|Loading Induced Fluid Flow and Disuse Bone Loss]]
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-	~~[[Jacobs:Research:Microfabrication of 3D Microfluidic Environments for Osteocytes\|Microfabrication of 3D Microfluidic Environments for Osteocytes]]~~

	[[Jacobs:Research:Structural Analysis of Cytoskeletal Deformation in Bone Cells Exposed to Shear Stress\|Structural Analysis of Cytoskeletal Deformation in Bone Cells Exposed to Shear Stress]]		[[Jacobs:Research:Structural Analysis of Cytoskeletal Deformation in Bone Cells Exposed to Shear Stress\|Structural Analysis of Cytoskeletal Deformation in Bone Cells Exposed to Shear Stress]]

An M. Nguyen at 22:52, 2 December 2011

An M. Nguyen — Fri, 02 Dec 2011 22:52:06 GMT

←Older revision		Revision as of 22:52, 2 December 2011
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	<div style="padding: 10px; width: 710px; border: 5px solid #000000;">		<div style="padding: 10px; width: 710px; border: 5px solid #000000;">
-	The overall focus of the CMBL group is to understand how cells sense and respond to changes in their mechanical environment. Although a wide range of tissues are known to be regulated by physical signals, outside of sensory mechanisms, the cellular aparatus responsible for the initial "mechanotransduction" event is poorly understood. Our group is primarily focused on mechanosensitivity of bone cells as it relates to osteoporosis, stress fractures, and disuse bone loss associated with spinal cord injury and space flight. We have identified the cellular level flow of fluid due to loading as a potent physical signal in cellular metabolism~~. Our research has been funded by a variety of sources including the NIH, NASA, NSF, US Army, Department of Veterans Affairs, and the Whitaker Foundation~~.	+	The overall focus of the CMBL group is to understand how cells sense and respond to changes in their mechanical environment. Although a wide range of tissues are known to be regulated by physical signals, outside of sensory mechanisms, the cellular aparatus responsible for the initial "mechanotransduction" event is poorly understood. Our group is primarily focused on mechanosensitivity of bone cells as it relates to osteoporosis, stress fractures, and disuse bone loss associated with spinal cord injury and space flight. We have identified the cellular level flow of fluid due to loading as a potent physical signal in cellular metabolism.

	=== Active Projects ===		=== Active Projects ===

An M. Nguyen at 23:47, 4 March 2011

An M. Nguyen — Fri, 04 Mar 2011 23:47:21 GMT

←Older revision		Revision as of 23:47, 4 March 2011
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	{{Template:Jacobs}}		{{Template:Jacobs}}
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		+	<div style="padding: 10px; width: 710px; border: 5px solid #000000;">
	The overall focus of the CMBL group is to understand how cells sense and respond to changes in their mechanical environment. Although a wide range of tissues are known to be regulated by physical signals, outside of sensory mechanisms, the cellular aparatus responsible for the initial "mechanotransduction" event is poorly understood. Our group is primarily focused on mechanosensitivity of bone cells as it relates to osteoporosis, stress fractures, and disuse bone loss associated with spinal cord injury and space flight. We have identified the cellular level flow of fluid due to loading as a potent physical signal in cellular metabolism. Our research has been funded by a variety of sources including the NIH, NASA, NSF, US Army, Department of Veterans Affairs, and the Whitaker Foundation.		The overall focus of the CMBL group is to understand how cells sense and respond to changes in their mechanical environment. Although a wide range of tissues are known to be regulated by physical signals, outside of sensory mechanisms, the cellular aparatus responsible for the initial "mechanotransduction" event is poorly understood. Our group is primarily focused on mechanosensitivity of bone cells as it relates to osteoporosis, stress fractures, and disuse bone loss associated with spinal cord injury and space flight. We have identified the cellular level flow of fluid due to loading as a potent physical signal in cellular metabolism. Our research has been funded by a variety of sources including the NIH, NASA, NSF, US Army, Department of Veterans Affairs, and the Whitaker Foundation.

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	Our research has been funded by a variety of sources including the NIH, NASA, NSF, US Army, Department of Veterans Affairs, and the Whitaker Foundation.		Our research has been funded by a variety of sources including the NIH, NASA, NSF, US Army, Department of Veterans Affairs, and the Whitaker Foundation.
		+	</div>

Ashley Chou: /* Active Projects */

Ashley Chou — Tue, 15 Jul 2008 16:27:37 GMT

Active Projects

←Older revision		Revision as of 16:27, 15 July 2008
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	[[Jacobs:Research:Cellular Basis for Optimal Osteogenic Physical Interventions\|Cellular Basis for Optimal Osteogenic Physical Interventions]]		[[Jacobs:Research:Cellular Basis for Optimal Osteogenic Physical Interventions\|Cellular Basis for Optimal Osteogenic Physical Interventions]]
		+
		+
		+	Our research has been funded by a variety of sources including the NIH, NASA, NSF, US Army, Department of Veterans Affairs, and the Whitaker Foundation.

Ashley Chou: /* Active Projects */

Ashley Chou — Tue, 15 Jul 2008 16:27:19 GMT

Active Projects

←Older revision		Revision as of 16:27, 15 July 2008
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	[[Jacobs:Research:Structural Analysis of Cytoskeletal Deformation in Bone Cells Exposed to Shear Stress\|Structural Analysis of Cytoskeletal Deformation in Bone Cells Exposed to Shear Stress]]		[[Jacobs:Research:Structural Analysis of Cytoskeletal Deformation in Bone Cells Exposed to Shear Stress\|Structural Analysis of Cytoskeletal Deformation in Bone Cells Exposed to Shear Stress]]
		+
		+	[[Jacobs:Research:Cellular Basis for Optimal Osteogenic Physical Interventions\|Cellular Basis for Optimal Osteogenic Physical Interventions]]

Ashley Chou: /* Active Projects */

Ashley Chou — Tue, 15 Jul 2008 16:24:18 GMT

Active Projects

←Older revision		Revision as of 16:24, 15 July 2008
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	[[Jacobs:Research:Microfabrication of 3D Microfluidic Environments for Osteocytes\|Microfabrication of 3D Microfluidic Environments for Osteocytes]]		[[Jacobs:Research:Microfabrication of 3D Microfluidic Environments for Osteocytes\|Microfabrication of 3D Microfluidic Environments for Osteocytes]]
		+
		+	[[Jacobs:Research:Structural Analysis of Cytoskeletal Deformation in Bone Cells Exposed to Shear Stress\|Structural Analysis of Cytoskeletal Deformation in Bone Cells Exposed to Shear Stress]]

Ashley Chou: /* Active Projects */

Ashley Chou — Tue, 15 Jul 2008 16:21:45 GMT

Active Projects

←Older revision		Revision as of 16:21, 15 July 2008
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	[[Jacobs:Research:Loading Induced Fluid Flow and Disuse Bone Loss\|Loading Induced Fluid Flow and Disuse Bone Loss]]		[[Jacobs:Research:Loading Induced Fluid Flow and Disuse Bone Loss\|Loading Induced Fluid Flow and Disuse Bone Loss]]
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		+	[[Jacobs:Research:Microfabrication of 3D Microfluidic Environments for Osteocytes\|Microfabrication of 3D Microfluidic Environments for Osteocytes]]

Ashley Chou: /* Active Projects */

Ashley Chou — Tue, 15 Jul 2008 16:18:44 GMT

Active Projects

←Older revision		Revision as of 16:18, 15 July 2008
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	[[Jacobs:Research:Mechanotransduction in Bone via Oscillatory Fluid Flow\|Mechanotransduction in Bone via Oscillatory Fluid Flow]]		[[Jacobs:Research:Mechanotransduction in Bone via Oscillatory Fluid Flow\|Mechanotransduction in Bone via Oscillatory Fluid Flow]]
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		+	[[Jacobs:Research:Loading Induced Fluid Flow and Disuse Bone Loss\|Loading Induced Fluid Flow and Disuse Bone Loss]]

Ashley Chou: /* Active Projects */

Ashley Chou — Tue, 15 Jul 2008 16:16:23 GMT

Active Projects

←Older revision		Revision as of 16:16, 15 July 2008
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	=== Active Projects ===		=== Active Projects ===
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		+	[[Jacobs:Research:Mechanotransduction in Bone via Oscillatory Fluid Flow\|Mechanotransduction in Bone via Oscillatory Fluid Flow]]

Christopher Jacobs: New page: {{Template:Jacobs}} The overall focus of the CMBL group is to understand how cells sense and respond to changes in their mechanical environment. Although a wide range of tissues are known ...

Christopher Jacobs — Mon, 21 Apr 2008 19:16:09 GMT

New page: {{Template:Jacobs}} The overall focus of the CMBL group is to understand how cells sense and respond to changes in their mechanical environment. Although a wide range of tissues are known ...

New page

{{Template:Jacobs}}
The overall focus of the CMBL group is to understand how cells sense and respond to changes in their mechanical environment. Although a wide range of tissues are known to be regulated by physical signals, outside of sensory mechanisms, the cellular aparatus responsible for the initial "mechanotransduction" event is poorly understood. Our group is primarily focused on mechanosensitivity of bone cells as it relates to osteoporosis, stress fractures, and disuse bone loss associated with spinal cord injury and space flight. We have identified the cellular level flow of fluid due to loading as a potent physical signal in cellular metabolism. Our research has been funded by a variety of sources including the NIH, NASA, NSF, US Army, Department of Veterans Affairs, and the Whitaker Foundation.

=== Active Projects ===

←Older revision		Revision as of 22:55, 2 December 2011
Line 9:		Line 9:

	[[Jacobs:Research:Loading Induced Fluid Flow and Disuse Bone Loss\|Loading Induced Fluid Flow and Disuse Bone Loss]]		[[Jacobs:Research:Loading Induced Fluid Flow and Disuse Bone Loss\|Loading Induced Fluid Flow and Disuse Bone Loss]]
-
-	~~[[Jacobs:Research:Microfabrication of 3D Microfluidic Environments for Osteocytes\|Microfabrication of 3D Microfluidic Environments for Osteocytes]]~~

	[[Jacobs:Research:Structural Analysis of Cytoskeletal Deformation in Bone Cells Exposed to Shear Stress\|Structural Analysis of Cytoskeletal Deformation in Bone Cells Exposed to Shear Stress]]		[[Jacobs:Research:Structural Analysis of Cytoskeletal Deformation in Bone Cells Exposed to Shear Stress\|Structural Analysis of Cytoskeletal Deformation in Bone Cells Exposed to Shear Stress]]